Trials Sponsors Conditions Drugs Pricing

Conditions

Eosinophilic Esophagitis (EoE)Functional Dyspepsia Gastroesophageal Reflux Disease (GERD)

Keywords

GERDEGDpH testingeosinophilic esophagitisimpedance testing

Outcome Measures

Primary Outcomes (2)

Number of Patients with GERD and/or Eosinophilic Esophagitis(EoE)
Mucosal impedance will be obtained during standard of care endoscopy and results will be available immediately. For those patients who may be undergoing ph monitoring as standard of care, those data will be compared to the mucosal impedance values obtained at bedside.
5 minutes
Mucosal impedance values correspond with histopathologic diagnosis in patients with EoE
5 minutes

Study Arms (1)

EGD with Biopsy

Pediatric patients scheduled for standard of care EGD with biopsy also received measurement of mucosal impedance

Diagnostic Test: Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedance

Interventions

Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedanceDiagnostic test

EGD with Biopsy

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age1 Year - 18 Years

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64)

Sampling MethodProbability Sample

Study Population

Pediatric patients of our Vanderbilt Pediatric Gastroenterology Clinic undergoing routine evaluation of dyspepsia with endoscopy that meet the inclusion/exclusion criteria as defined above.

You may qualify if:

Patients between 1 year and 18 years of age

Sponsors & Collaborators

Vanderbilt University Medical Center
Otherlead
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIHcollaborator

Study Sites (1)

Vanderbilt Children's Hospital

Nashville, Tennessee, 37232, United States

MeSH Terms

Conditions

Gastroesophageal RefluxEosinophilic Esophagitis

Interventions

Endoscopy, Digestive System

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesEsophagitisGastroenteritisEosinophiliaLeukocyte DisordersHematologic DiseasesHemic and Lymphatic Diseases

Study Officials

Mary Allyson Lowry, MD
Vanderbilt University Medical Center
PRINCIPAL INVESTIGATOR
Sari Acra, MD
Vanderbilt University Medical Center
PRINCIPAL INVESTIGATOR
Michael Vaezi, MD, PhD
Vanderbilt University Medical Center
PRINCIPAL INVESTIGATOR

Enrollment

127 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE ONLY
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Co-Principal Investigator

Study Record Dates

First Submitted

July 14, 2014

First Posted

December 19, 2014

Study Start

August 2014

Date type not reported

This date has not been verified as actual or estimated.

Mucosal Impedance in Pediatric Population

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (1)

EGD with Biopsy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Study Arms (1)

EGD with Biopsy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations