NCT02311309

Brief Summary

Peroperative bleeding has been studied in specific populations exposed to bleeding (i.e. cardiac surgery, orthopedic surgery). Epidemiology of peroperative bleeding and transfusion remain poorly studied in the whole cohort of patients scheduled for surgery remain unknown. The investigators conducted a prospective study in order to examine the incidence, and risk factors associated with peroperative bleeding and transfusion.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,439

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2013

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2014

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

December 4, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 8, 2014

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

April 21, 2016

Completed
Last Updated

April 21, 2016

Status Verified

March 1, 2016

Enrollment Period

4 months

First QC Date

December 4, 2014

Results QC Date

February 9, 2016

Last Update Submit

March 22, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Unanticipated Bleeding

    From arrival in operating room until the patients leave post anesthesia care unit

    one day

Secondary Outcomes (3)

  • Transfusions

    one day

  • Preoperative Anemia

    one day

  • Lowest Hemoglobin

    one day

Study Arms (2)

control

Patients with either transfusion with pre ordered packed red blood cells or hemoglobin concentration \> 8 g/dL.

Other: Control

unanticipated bleeding

Unanticipated bleeding was defined as either transfusion above the pre ordered packed red blood cells or hemoglobin concentration \< 8 g/dL.

Other: Unanticipated bleeding

Interventions

ControlOTHER

Control patients were defined as either transfusion using only pre ordered packed red blood cells or peroperative hemoglobin concentration \>8 g/dL.

control

Unanticipated bleeding was defined as either transfusion above the pre ordered packed red blood cells or peroperative hemoglobin concentration \< 8 g/dL.

unanticipated bleeding

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Consecutive patients scheduled for surgery (expect cardiac, pediatric, and emergency surgery)

You may qualify if:

  • Patient scheduled for non cardiac and non emergency surgery

You may not qualify if:

  • Cardiac surgery
  • Emergency surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hemorrhage

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Dr Jean-Luc Hanouz
Organization
CHU de Caen

Study Officials

  • Jean-Luc Hanouz, M.D.,Ph.D.

    University Hospital, Caen

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 4, 2014

First Posted

December 8, 2014

Study Start

November 1, 2013

Primary Completion

March 1, 2014

Study Completion

March 1, 2014

Last Updated

April 21, 2016

Results First Posted

April 21, 2016

Record last verified: 2016-03