NCT02301637

Brief Summary

The purpose of this clinical trial is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) for ongoing development and validation of the Eeva System.

Trial Health

47
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2014

Geographic Reach
2 countries

7 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 18, 2014

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 26, 2014

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

July 13, 2015

Status Verified

July 1, 2015

Enrollment Period

1.2 years

First QC Date

November 18, 2014

Last Update Submit

July 9, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Adverse events and device malfunctions will be reported and summarized from the point of Eeva imaging through study exit.

    36 months

Interventions

The Eeva System is indicated to provide adjunctive information on events occurring during the first two days of development that may predict further development to the blastocyst stage on Day 5 of development. This adjunctive information aids in the selection of embryo(s) for transfer on Day 3 when, following morphological assessment on Day 3, there are multiple embryos deemed suitable for transfer or freezing.

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing in vitro fertilization treatment who fulfill all eligibility criteria.

You may qualify if:

  • At least 18 years of age
  • Women undergoing in vitro fertilization treatment using their own eggs
  • Fresh or Frozen Blastocyst (Day 5-6) transfer
  • At least 5 diploid (2PN) embryos at fertilization check
  • Willing to have all 2PN embryos imaged by Eeva
  • Willing to comply with study protocol and procedures
  • Willing to provide written informed consent

You may not qualify if:

  • Freeze-all due to ovarian hyperstimulation syndrome (OHSS)
  • Use of donor egg / gestational carrier
  • Fertilization using surgically removed sperm
  • History of cancer
  • Assisted Hatching (AH) on Day 3

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

FCI (River North)

Chicago, Illinois, 60610, United States

Location

Midwest Fertility Specialists

Carmel, Indiana, 46032, United States

Location

University of Iowa

Iowa City, Iowa, 52242, United States

Location

Texas Fertility Center

Austin, Texas, 78731, United States

Location

Houston Fertility Institute

Houston, Texas, 77063, United States

Location

Seattle Reproductive Medicine

Seatlle, Washington, 98109, United States

Location

Fertility Associates

Wellington, 6011, New Zealand

Location

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • Sheua Shen, MD

    Vice President, Scientific and Medical Affairs

    STUDY CHAIR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 18, 2014

First Posted

November 26, 2014

Study Start

October 1, 2014

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

July 13, 2015

Record last verified: 2015-07

Locations