The Pre-operative Pathway in Pancreatic Head Malignancy-assessment of the Diagnostic Accuracy of Staging CT Scan

NCT02296736 | Completed

• 2 other identifiers: 14/P/09014/SC/1391 PR
• Study Type: observational
• Target: 422
• Locations: 1 country
• Sites: 1

Brief Summary

Our aim is to assess the ability of scans to distinguish the organ of origin of pancreatic head malignant tumours and to predict the resectability based on the preoperative imaging. To achieve this, a retrospective review of the preoperative CT scans will be conducted for all patients with pancreatic head malignancy treated at the Peninsula Hepato-Pancreatico-Biliary (HPB) cancer unit between January 2006 till January 2014.

Conditions

Cancer of Pancreas

Keywords

computerised tomography (CT) scan; diagnostic accuracy; Pancreatic head malignancy

Outcome Measures

Primary Outcomes (1)

• Review pre-operative imaging to distinguish the organ of origin of pancreatic head tumours

  Retrospective review of imaging of patients who have undergone surgery for presumed pancreatic malignancy

  8 years

Secondary Outcomes (1)

• Resectabilty of the pancreatic tumour

  8 years

Study Arms (1)

Pancreatic malignancy

All patients who have undergone surgery for presumed pancreatic malignancy in Derriford Hospital between Jan 2006 and Jan 14 and had a Computerised tomography (CT) scan.

Radiation: Computerised tomography (CT) scan

Interventions

Computerised tomography (CT) scan RADIATION

Retrospective review of CT scans

Pancreatic malignancy

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Retrospective review of imaging of all patients who have undergone surgery for presumed pancreatic malignancy in Derriford Hospital.

You may qualify if:

• All patients who have undergone surgery for presumed pancreatic malignancy in Derriford Hospital between Jan 2006 and Jan 14 will be included.

You may not qualify if:

• Not applicable

Sponsors & Collaborators

• University Hospital Plymouth NHS Trust: lead

Study Sites (1)

Plymouth Hospitals NHS Trust

Plymouth, Devon, PL6 8BX, United Kingdom

Location

Related Publications (1)

• Amr B, Shahtahmassebi G, Aroori S, Bowles MJ, Briggs CD, Stell DA. Variation in survival after surgery for peri-ampullary cancer in a regional cancer network. BMC Surg. 2017 Mar 7;17(1):23. doi: 10.1186/s12893-017-0220-3.

  PMID: 28270136 DERIVED

MeSH Terms

Conditions

Pancreatic Neoplasms

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Pancreatic Diseases; Endocrine System Diseases

Study Officials

• David Stell, MBBS, PhD

  University Hospital Plymouth NHS Trust

  STUDY DIRECTOR

• Bassem Amr, MBBS

  University Hospital Plymouth NHS Trust

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 18, 2014
• First Posted: November 20, 2014
• Study Start: October 1, 2014
• Primary Completion: September 1, 2017
• Study Completion: September 1, 2017
• Last Updated: September 4, 2019

Record last verified: 2019-09

Locations

GB (1)