NCT02288650

Brief Summary

At the child, the post-operative vomitings (POV) remain the main post-operative complication in term of frequency. They also represent the first cause of unforeseen hospitalization in day case surgery. The causes of POV are multiple, including in particular the post-operative prescription of opioids. The role of the premature refeeding remains discussed. Up to the age of 4 years, acute pain is difficult to distinguish from other causes of distress (anxiety, anger but also hunger) being able to make prescribe wrongly opioids in post-operative. The main objective of this study is to estimate the POV in pediatric day case surgery after early refeeding with clear liquids in the recovery room or only in the day case wards (usual practice). The secondary objectives are to estimate the time on returning to the day case ward, at home, the post-operative opioid consumption, early refeeding adverse effects (desaturation, swallowing trouble)

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
808

participants targeted

Target at P75+ for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

July 25, 2013

Completed
1.3 years until next milestone

First Posted

Study publicly available on registry

November 11, 2014

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
Last Updated

November 11, 2014

Status Verified

November 1, 2014

Enrollment Period

2 years

First QC Date

July 25, 2013

Last Update Submit

November 6, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Time between withdrawal of orotracheal tube and POV

    The participant are followed for 3 days.

Study Arms (2)

Liberal group

EXPERIMENTAL

Early refeeding

Other: early refeeding

Control group

SHAM COMPARATOR

Refeeding in the day case ward (usual practice)

Other: refeeding only in the recovery room (usual practice).

Interventions

Eligibility Criteria

Age3 Months - 4 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Patient of less than 4 years old
  • A pediatric day case surgery scheduled

You may not qualify if:

  • Child lower age or 3 month old equal
  • Premature child of conceptional age lower than 60 weeks
  • Anesthetic or surgical constraint dissuading day case surgery or early refeeding
  • Digestive pathology predisposing to the VPO (Hernia hiatal, gastro-oesophageal reflux)
  • treatment interfering with emesis (imidazoles, neuroleptic)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hôpitaux Universitaires de Strasbourg

Strasbourg, France

RECRUITING

Related Publications (1)

  • Chauvin C, Schalber-Geyer AS, Lefebvre F, Bopp C, Carrenard G, Marcoux L, Mayer JF, Schwaab C, Joshi GP, Diemunsch P. Early postoperative oral fluid intake in paediatric day case surgery influences the need for opioids and postoperative vomiting: a controlled randomized trialdagger. Br J Anaesth. 2017 Mar 1;118(3):407-414. doi: 10.1093/bja/aew463.

Central Study Contacts

Chloé CHAUVIN, Doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 25, 2013

First Posted

November 11, 2014

Study Start

July 1, 2013

Primary Completion

July 1, 2015

Last Updated

November 11, 2014

Record last verified: 2014-11

Locations