NCT02287324

Brief Summary

The purpose of the study is to see if manipulation of the neck will change the way people who may or may not have neck pain, walk under differing conditions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 4, 2014

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
3 months until next milestone

First Posted

Study publicly available on registry

November 10, 2014

Completed
Last Updated

November 10, 2014

Status Verified

November 1, 2014

Enrollment Period

7 months

First QC Date

March 4, 2014

Last Update Submit

November 5, 2014

Conditions

Keywords

Cervicalgia

Outcome Measures

Primary Outcomes (1)

  • Gait Parameters - Composite Score

    A composite score derived from specific gait parameters which include stride length, step length, step width, cadence

    Up to 10 minutes after intervention

Secondary Outcomes (1)

  • Global Rating of Change Scale

    Up to 10 minutes after intervention

Study Arms (2)

Manipulation

ACTIVE COMPARATOR

High velocity low amplitude thrust joint manipulation to the cervical spine

Procedure: Manipulation

Manual Contact

PLACEBO COMPARATOR

Manual contact to suboccipital region of the cervical spine for 5 minutes

Procedure: Manual Contact

Interventions

ManipulationPROCEDURE
Manipulation
Manual Contact

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Volunteers may or may not have mechanical neck pain
  • Aged 18 to 70 years
  • If neck pain is present, must have Neck Disability Index score of at least 10 out of 50 points

You may not qualify if:

  • 'Red flag' items indicated in Neck Medical Screening Questionnaire such as history of a tumor, bone fracture, metabolic diseases, Rheumatoid Arthritis, osteoporosis, severe atherosclerosis, prolonged history of steroid use, etc.
  • History of neck whiplash injury
  • Diagnosis from physician of cervical spinal stenosis (narrowing of spinal canal) or presence of symptoms (pain, pins and needles, numbness) down both arms
  • Presence of central nervous system involvement such as exaggerated reflexes, changes in sensation in the hands, muscle wasting in the hands, impaired sensation of the face, altered taste, and presence of abnormal reflexes
  • Evidence of neurological signs consistent with nerve root entrapment (pinched nerve in the neck)
  • Prior surgery to neck or upper back
  • A medical condition which may influence assessment of pain or pressure pain thresholds (i.e. taking analgesics, sedatives, history of substance abuse, or cognitive deficiency)
  • Diagnosis from your physician of fibromyalgia syndrome
  • Currently pregnant, or could be pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UNLV

Las Vegas, Nevada, 89154, United States

Location

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 4, 2014

First Posted

November 10, 2014

Study Start

January 1, 2014

Primary Completion

August 1, 2014

Study Completion

August 1, 2014

Last Updated

November 10, 2014

Record last verified: 2014-11

Locations