NCT02285803

Brief Summary

The aim of this study is to evaluate the added effect of tDCS to TRT within patients with chronic, non-pulsatile tinnitus. Patients were randomised in two groups namely, TRT and real tDCS and the second one is TRT with sham tDCS. Evaluations took place at the start of therapy, at the end of the counselling and at last a follow-up visit will be planned after 84 days of the start of the therapy. Subjective outcome measurements such as Tinnitus Functional Index and Visual Analogue Scales of loudness are the primary outcome measurement. Secondary outcome measurements are the Hospital Anxiety and Depression Scale, hyperacusis questionnaire and psychoacoustic measurements.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Nov 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 31, 2014

Completed
1 day until next milestone

Study Start

First participant enrolled

November 1, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 7, 2014

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

April 18, 2016

Status Verified

April 1, 2016

Enrollment Period

1.3 years

First QC Date

October 31, 2014

Last Update Submit

April 14, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Tinnitus Functional Index (TFI)

    3 months

Secondary Outcomes (6)

  • Hyperacusis Questionnaire

    3 months

  • Hospital Anxiety and depression Scale

    3 months

  • Patient Global Impression of Change

    3 months

  • Psychoacoustic measurements

    3 months

  • Late Latency Evoked Potentials

    3 months

  • +1 more secondary outcomes

Study Arms (2)

TRT and real tDCS

ACTIVE COMPARATOR
Device: transcranial direct current stimulation (tDCS)

TRT and sham tDCS

SHAM COMPARATOR
Device: transcranial direct current stimulation (tDCS)

Interventions

TRT and real tDCSTRT and sham tDCS

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Duration of tinnitus \> 6 months
  • Maximum loudness of tinnitus on the VAS ≥ 4
  • TFI score ≥ 25

You may not qualify if:

  • Pregnancy
  • Psychiatric disorders
  • Pace maker or defibrillator
  • Pulsatile tinnitus
  • Acoustic Neurinoma
  • CVA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University hospital of Antwerp

Edegem, Antwerp, 2650, Belgium

Location

Related Publications (1)

  • Rabau S, Van Rompaey V, Van de Heyning P. The effect of Transcranial Direct Current Stimulation in addition to Tinnitus Retraining Therapy for treatment of chronic tinnitus patients: a study protocol for a double-blind controlled randomised trial. Trials. 2015 Nov 10;16:514. doi: 10.1186/s13063-015-1041-2.

MeSH Terms

Conditions

Tinnitus

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsConvulsive TherapyPsychiatric Somatic TherapiesBehavioral Disciplines and ActivitiesElectroshockPsychological Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof.

Study Record Dates

First Submitted

October 31, 2014

First Posted

November 7, 2014

Study Start

November 1, 2014

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

April 18, 2016

Record last verified: 2016-04

Locations