NCT02284841

Brief Summary

This study evaluates the efficacy of Hilotherm therapy on the incidence of swelling and pain following the surgical removal of lower wisdom teeth. All participants will have two lower wisdom teeth removed, with the Hilotherm cooling face mask only applied to one side of the patients' face for 60 minutes post-operatively, thus the patient being their own control.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2015

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 9, 2014

Completed
28 days until next milestone

First Posted

Study publicly available on registry

November 6, 2014

Completed
9 months until next milestone

Study Start

First participant enrolled

August 1, 2015

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

September 3, 2015

Status Verified

August 1, 2015

Enrollment Period

4 months

First QC Date

October 9, 2014

Last Update Submit

September 2, 2015

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in post-operative swelling using 3D photography analysis

    Extent of swelling on the side of wisdom tooth removal with the intervention compared with the side without the intervention

    Day 0 (pre/60 min post op), Days 3, 10, 24.

  • Change in pain intensity using visual analogue scale

    Self-reported pain intensity using visual analogue scale at time intervals as above, comparing the side of wisdom tooth removal with intervention vs the side of wisdom tooth removal without intervention

    Day 0 (60 min post-op), Days 3, 10, 24.

Secondary Outcomes (1)

  • Patient satisfaction

    Day 24

Study Arms (2)

Hilotherm cooling face mask

EXPERIMENTAL

Use of Hilotherm cooling face mask post-operatively following surgical wisdom tooth removal to evaluate the incidence of pain and swelling

Device: Hilotherm cooling face mask

No Hilotherm

NO INTERVENTION

No intervention following surgical wisdom tooth removal (same patient), therefore the patient is their own control.

Interventions

Hilotherapy - use of an external cooling device; a facial mask through which water circulates at a controlled temperature, allowing continuous cooling of the face, and is thought to reduce post-operative swelling and pain.

Hilotherm cooling face mask

Eligibility Criteria

Age16 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • any patients requiring bilateral lower third molars extracted of similar technical difficulty under general anaesthesia

You may not qualify if:

  • any intra-operative complications
  • any post-operative complications, including infection
  • if the extractions end up being too dissimilar surgically
  • any contra-indication to the Hilotherm mask
  • patients with any immune system-affecting diseases
  • patients with allergies to pharmaceutical drugs (eg. analgesics or antibiotics)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Queen Marys Hospital, Kings College London NHS Foundation Trust

Sidcup, Kent, DA146LT, United Kingdom

RECRUITING

Study Officials

  • Kathy Fan, PhD, FDSRSC, FRCSEd, FRCS OMFS

    Kings College Hospital NHS Foundation Trust

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Kathy Fan, PhD, FDSRSC, FRCSEd, FRCS OMFS

CONTACT

Meera Pajpani, BDS MJDF RCS Eng

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 9, 2014

First Posted

November 6, 2014

Study Start

August 1, 2015

Primary Completion

December 1, 2015

Study Completion

July 1, 2016

Last Updated

September 3, 2015

Record last verified: 2015-08

Locations