Neuropathic Pain and Quality of Life in ICU Survivors

NCT02279212 | Completed

• 1 other identifier: S-07505b (REK)
• Study Type: observational
• Target: 127
• Locations: 1 country
• Sites: 1

Brief Summary

Previous research on intensive care unit (ICU) survivors shows that rehabilitation is challenging, because of patients experiences of disease related problems both under and after treatment. Approximately 20 % of patients die within hospital, up to 80% suffer from hallucinations and nightmares, deal with paranoiac experiences, chronic pain and other symptoms and disability (Angus et al 2004; De Letter et al 2001; Ely et al 2001; Nelson et al 2006; Van den Berghe et al 2001; Van den Berghe et al 2003) . A recent study shows that 28% of intensive care survivors have chronic pain that reduce their health related quality of life (Boyle et al 2004). The aim of this study is to perform a survey about prevalence of pain type, and which consequences this causes when it comes to function and quality of life up to 12 months after the ICU stay.

1. 1.What type of pain has ICU survivors and how do pain change over time, related to treatment/rehabilitation and the illness' development?
2. 2.What is the relationship between different pain characteristic, quality of life, anxiety, depression, fatigue, sleep and PTSD in these patients?
3. 3.What is these patients largest obstacle for good QoL after discharge from hospital?

Conditions

Critical Illness

Keywords

Critical illness; pain; quality of life

Outcome Measures

Primary Outcomes (1)

• Do pain change over time in ICU survivors meassured with BPI and NPSI?

  We will compare the results from 3 months with 1 year and look for differences.

  1year after ICU discharge

Secondary Outcomes (4)

• What is the relationship between patients self reported experience of pain and neurophysiological findings?

  3 months after ICU discharge

• What is the relationship between patients self reported experience of pain and neurophysiological findings?

  1 year after ICU discharge

• How are ICU survivors health related quality of life meassured with SF12?

  3 months after ICU discharge

• How are ICU survivors health related quality of life meassured with SF 12?

  1 year after ICU discharge

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients in a Norwegian ICU. Medical and surgical patients, no thorasic surgery or trauma.

You may qualify if:

• ICU stay longer than 48 h
• years old or older
• Patients must write and understand Norwegian well.

You may not qualify if:

• Dying patients
• No acceptance form next of kind
• No concent from the patients
• Other that the researcher thinks should be excluded f. ex Patients with very bad prognosis
• Patients with low probability for self report after ICU stay

Sponsors & Collaborators

• Oslo University Hospital: lead

Study Sites (1)

Oslo University Hospital

Oslo, 0424, Norway

Location

Related Publications (1)

• Langerud AK, Rustoen T, Smastuen MC, Kongsgaard U, Stubhaug A. Intensive care survivor-reported symptoms: a longitudinal study of survivors' symptoms. Nurs Crit Care. 2018 Jan;23(1):48-54. doi: 10.1111/nicc.12330. Epub 2017 Dec 15.

  PMID: 29243344 DERIVED

MeSH Terms

Conditions

Critical Illness; Pain

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Audun Stubhaug, MD PhD

  Oslo University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MNSc

Study Record Dates

• First Submitted: December 6, 2010
• First Posted: October 31, 2014
• Study Start: May 1, 2010
• Primary Completion: April 30, 2018
• Study Completion: September 6, 2018
• Last Updated: March 4, 2020

Record last verified: 2020-03

Locations

NO (1)