NCT02264275

Brief Summary

The purpose of this study is to determine if aerobic exercise training can serve as comprehensive palliative care, whereby enhancing cardiovascular fitness, mitigating depressive symptoms and augmenting sleep while bolstering health related quality of life in youth with Crohn's Disease and Ulcerative Colitis.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

October 8, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 15, 2014

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2015

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
Last Updated

October 21, 2014

Status Verified

October 1, 2014

Enrollment Period

4 months

First QC Date

October 8, 2014

Last Update Submit

October 20, 2014

Conditions

Keywords

Aerobic ExerciseExerciseExergameBehaviorVideo GameInflammatory Bowel DiseaseChildrenAdolescentsPediatricPhysical Fitness

Outcome Measures

Primary Outcomes (1)

  • Pediatric Disease Activity Index

    Uses either Crohn's Disease or Ulcerative Colitis Disease Activity Index respective to the patient's disease

    8 Weeks

Secondary Outcomes (4)

  • Sleep

    8 Weeks

  • Depressive Symptomology

    8 Weeks

  • Health Related Quality of Life

    8 Weeks

  • Estimation of Vo2Max

    8 Weeks

Study Arms (1)

Aerobic Exercise Training

EXPERIMENTAL

An 8-week Nintendo Wii at-home dancing exergame Intervention

Behavioral: Aerobic Exercise Training

Interventions

The aerobic exercise training uses a television attached to a Nintendo Wii videogame console with a dance game to be played by participants on 5 days per week using a ramped-duration schedule (from 10-30 minutes of moderate physical activity daily).

Also known as: Nintendo Wii, Exergame, Dance Videogame
Aerobic Exercise Training

Eligibility Criteria

Age7 Years - 20 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • aged 7 through 20 at start of study
  • willing and able to volunteer in the study
  • able to communicate and to complete questionnaires in German
  • have a functioning television with Nintendo Wii compatibility at home
  • provide participant written informed consent (when ≥11 years old at start of study)
  • provide parental/legal caregiver written informed consent (when participant is ≤17 years old at start of study)
  • provide oral informed consent (when ≤10 years old at start of study)

You may not qualify if:

  • refusal to give necessary oral or written informed consent by patient and/or parent (legal caregiver)
  • not aged 7 through 20 at start of study
  • not willing and able to volunteer in the study
  • has sibling enrolled in this study
  • has severe physical diseases of the locomotor apparatus, psychotic disorders, severe affective disorders, eating disorders, mental retardation, autism spectrum disorder
  • inability to communicate and complete questionnaires in German
  • does not own a functional and Nintendo Wii-compatible television at home
  • among female adolescents, pregnancy, breastfeeding or intention to get pregnant during the study
  • has clinically significant cardiovascular disease
  • enrolment of the investigator, his/her family members, employees and other dependent persons

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Universitäre Psychiatrische Kliniken Basel (UPK)

Basel, Canton of Basel-City, 4012, Switzerland

RECRUITING

Universitäts-Kinderspital beider Basel (UKBB)

Basel, Canton of Basel-City, 4031, Switzerland

RECRUITING

Universität Basel (Departement für Sport, Bewegung und Gesundheit)

Basel, Canton of Basel-City, 4052, Switzerland

RECRUITING

Related Publications (2)

  • Mahlmann L, Gerber M, Furlano RI, Legeret C, Kalak N, Holsboer-Trachsler E, Brand S. Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls. BMC Gastroenterol. 2017 Dec 12;17(1):160. doi: 10.1186/s12876-017-0721-7.

  • Mahlmann L, Gerber M, Furlano RI, Legeret C, Kalak N, Holsboer-Trachsler E, Brand S. Impaired objective and subjective sleep in children and adolescents with inflammatory bowel disease compared to healthy controls. Sleep Med. 2017 Nov;39:25-31. doi: 10.1016/j.sleep.2017.08.015. Epub 2017 Sep 21.

Related Links

MeSH Terms

Conditions

Colitis, UlcerativeCrohn DiseaseDepressionMotor ActivityBehaviorInflammatory Bowel Diseases

Interventions

Exergaming

Condition Hierarchy (Ancestors)

ColitisGastroenteritisGastrointestinal DiseasesDigestive System DiseasesColonic DiseasesIntestinal DiseasesBehavioral Symptoms

Intervention Hierarchy (Ancestors)

ExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Catherine A Elliot, Dr. phil.

    University of Basel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Catherine A Elliot, Dr. phil.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Catherine Elliot

Study Record Dates

First Submitted

October 8, 2014

First Posted

October 15, 2014

Study Start

October 1, 2014

Primary Completion

February 1, 2015

Study Completion

March 1, 2015

Last Updated

October 21, 2014

Record last verified: 2014-10

Locations