NCT02256397

Brief Summary

The purpose of this study is to assess whether comprehensive care enhanced with new technology to optimize asthma care in the home (using both a special sensor to track inhaler use and a hand-held PIKO-1 device to assess patients' forced expiratory volume in the 1st second \[FEV1\]) is effective in reducing total days when medical treatment is given outside the home (in clinic, emergency department, or hospital) among children with severe asthma receiving comprehensive care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
63

participants targeted

Target at P25-P50 for not_applicable asthma

Timeline
Completed

Started Oct 2014

Typical duration for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2014

Completed
1 day until next milestone

Study Start

First participant enrolled

October 1, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 3, 2014

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2017

Completed
Last Updated

May 4, 2017

Status Verified

May 1, 2017

Enrollment Period

2.2 years

First QC Date

September 30, 2014

Last Update Submit

May 3, 2017

Conditions

Keywords

Asthma

Outcome Measures

Primary Outcomes (1)

  • Medical treatment outside of home

    Total number of days when medical treatment was given outside the home (in a clinic, ED, or hospital). Measured by parent report every 3 months for both groups.

    2 years

Secondary Outcomes (5)

  • Days of missed school

    2 years

  • Pulmonary Function Tests. (PFTs)

    2 years

  • Parental Satisfaction

    2 years

  • Total costs of clinic and hospital care

    2 years

  • Physician Services Cost to Reimbursement

    2 years

Study Arms (2)

Standard comprehensive care

ACTIVE COMPARATOR

Standard comprehensive care at High Risk Children's Clinic

Other: Standard comprehensive care

Enhanced comprehensive care

EXPERIMENTAL

standard comprehensive care at the High Risk Children's Clinic enhaced with new technologies: * If between 2 and 5 years old--\> will receive Home-centered comprehensive care with the propeller * 5 and above--\> will receive home-centered comprehensive care with propeller and PIKO

Other: Standard comprehensive careOther: enhanced comprehensive care

Interventions

Standard comprehensive care at High Risk Children's Clinic

Enhanced comprehensive careStandard comprehensive care

standard comprehensive care at the High Risk Children's Clinic enhaced with new technologies: * If between 2 and 5 years old--\> will receive Home-centered comprehensive care with the propeller * 5 and above--\> will receive home-centered comprehensive care with propeller and PIKO

Enhanced comprehensive care

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may not qualify if:

  • other major lung disease (e.g. cystic fibrosis or bronchopulmonary dysplasia) or neuromuscular impairment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

High Risk Children's Clinic

Houston, Texas, 77030, United States

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Ricardo A Mosquera, MD

    University of Texas Medical School in Houston

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Pediatrics

Study Record Dates

First Submitted

September 30, 2014

First Posted

October 3, 2014

Study Start

October 1, 2014

Primary Completion

December 1, 2016

Study Completion

April 1, 2017

Last Updated

May 4, 2017

Record last verified: 2017-05

Locations