NCT02254330

Brief Summary

The objectives of this study is to assess the characteristics and frequency of adenovirus conjunctivitis in a population of male and female patients from one year of age who present signs and symptoms of acute conjunctivitis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
386

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2014

Geographic Reach
1 country

25 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2014

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 29, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 1, 2014

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2015

Completed
Last Updated

January 10, 2017

Status Verified

January 1, 2017

Enrollment Period

1.1 years

First QC Date

September 29, 2014

Last Update Submit

January 9, 2017

Conditions

Keywords

Adenoviral conjunctivitis diagnosed with AdenoPlus™ Test

Outcome Measures

Primary Outcomes (1)

  • Frequency of patients with adenovirus conjunctivitis

    The percentage of patients with adenovirus conjunctivitis documented by a positive AdenoPlus® test over the tested population of male and female patients who present signs and symptoms of acute conjunctivitis.

    During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit)

Other Outcomes (5)

  • Seasonality and geographic repartition observed.

    During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit)

  • Clinical profiles of the patients

    During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit)

  • Resource utilization during the treatment and evaluation of the costs

    On day 1: at least once during the single visit to the ophthalmologist and if any also during the follow-up visit(s)

  • +2 more other outcomes

Eligibility Criteria

Age1 Year+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any female and male patients from one year of age with signs and symptoms of acute conjunctivitis either seen during ophthalmology consultations or who are in the emergency room or hospitalized, can be enrolled in the study

You may qualify if:

  • Male or Female patients of at least one year of age presenting acute (for less than 7 days) conjunctivitis signs and symptoms.
  • Patient or / and legal representative (if patient below 18 years of age) must be able to provide oral consent for the collection and treatment of the questionnaire data.
  • No history of hypersensitivity to corn starch, talcum powder or Dacron (sampling fleece components).

You may not qualify if:

  • Current use or having received (within the last 7 days) local antiviral therapies such as povidone iodine or ganciclovir, or topical steroids or immunomodulators such as cyclosporine which may interfere with the test result.
  • Previous enrolment in the present study.
  • Any direct involvement with the study conduct at site or any family link with study site staff.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (25)

VISSUM

Alicante, Spain

Location

Clinica Barraquer

Barcelona, Spain

Location

Hospital Clinic

Barcelona, Spain

Location

Instituto de Microcirugía Ocular

Barcelona, Spain

Location

Instituto Clínico Quirúrgico de Oftalmología

Bilbao, Spain

Location

Alcazar de San Juan

Ciudad Real, Spain

Location

Hospital La Arruzafa

Córdoba, Spain

Location

Ocumed Clinica Oftalmologica

Madrid, 28023, Spain

Location

Fundacion Jimenez Diaz

Madrid, Spain

Location

Hospital Clinico San Carlos

Madrid, Spain

Location

Hospital de Villalba

Madrid, Spain

Location

Hospital Infanta Leonor-Vallecas

Madrid, Spain

Location

Hospital La Paz

Madrid, Spain

Location

Hospital Quiron

Madrid, Spain

Location

Hospital Ramon Y Cajal

Madrid, Spain

Location

Hospital Torrejon

Madrid, Spain

Location

Instituto Oftalmologico Fernandez-Vega

Oviedo, Spain

Location

Clinica Universitaria de Navarra

Pamplona, Spain

Location

Hospital Universitario de Canarias

Santa Cruz de Tenerife, Spain

Location

Hospital Clinico Santiago de Compostela

Santiago de Compostela, Spain

Location

Hospital Clinico

Valencia, Spain

Location

Hospital La Fe

Valencia, Spain

Location

Hospital Clinico de Valladolid

Valladolid, Spain

Location

Instituto Oftalmobiologia Aplicada

Valladolid, Spain

Location

Hospital de Cruces, Baracaldo

Vizcaya, Spain

Location

MeSH Terms

Conditions

Conjunctivitis, Viral

Condition Hierarchy (Ancestors)

Eye Infections, ViralEye InfectionsInfectionsVirus DiseasesConjunctivitisConjunctival DiseasesEye Diseases

Study Officials

  • Jose Manuel Benitez Del Castillo, MD

    Ocumed Clinica Oftalmologica

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2014

First Posted

October 1, 2014

Study Start

July 1, 2014

Primary Completion

August 1, 2015

Study Completion

August 1, 2015

Last Updated

January 10, 2017

Record last verified: 2017-01

Locations