NCT02250638

Brief Summary

To obtain sufficient specimens and correlating clinical data from a well-controlled prospective clinical trial collecting longitudinal specimens from subjects diagnosed with any stage of pancreatic cancer.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
140

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2014

Longer than P75 for all trials

Geographic Reach
2 countries

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2014

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 24, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 26, 2014

Completed
6.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2021

Completed
Last Updated

August 17, 2021

Status Verified

July 1, 2020

Enrollment Period

7.2 years

First QC Date

September 24, 2014

Last Update Submit

August 16, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • A Prospective Longitudinal Study of CA 19-9 as an Aid in Monitoring Disease in Patients with Pancreatic Cancer

    3 years

Interventions

Physicians use the CA 19-9 test results to manage their patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Approximately 140 subjects will be enrolled in this study. Women and men greater than or equal to 18 years of age with a histologically/pathologically confirmed diagnosis of pancreatic cancer and a minimum of three serial blood draws collected at disease evaluation time points, as determined by the treating physician's standard of care, will be eligible.

You may qualify if:

  • Males and females, age≥ 18 years
  • Histologic/pathologic confirmation of exocrine pancreatic cancer
  • Any stage of disease: Newly diagnosed, stable, disease progression
  • Any treatment time point: Treatment naïve, currently receiving or completed therapy for pancreatic cancer including active monitoring.
  • Individuals with a history of malignant disease other than pancreatic cancer that was resected greater than 5 years ago and are currently in remission are eligible.
  • Life expectancy greater than 6 months
  • Able to understand and willing to provide informed consent

You may not qualify if:

  • Males and females, age \<18 years
  • No histologic/pathologic confirmation of exocrine pancreatic cancer
  • Life expectancy less than 6 months
  • Any concurrent malignancy other than basal or squamous cell skin cancers or in-situ cervical cancer.
  • Unable to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Boca Raton Regional Hospital

Boca Raton, Florida, 33486, United States

Location

Broward Health Medical Center

Fort Lauderdale, Florida, 33316, United States

Location

Harry & Jeanette Weinberg Cancer Institute

Baltimore, Maryland, 21237, United States

Location

Kansas City VA Center

Kansas City, Missouri, 64128, United States

Location

New Hanover Regional Medical Center

Wilmington, North Carolina, 28402, United States

Location

The Ohio State University

Columbus, Ohio, 43210, United States

Location

GI Research Institute

Vancouver, British Columbia, V6Z2K5, Canada

Location

Biospecimen

Retention: SAMPLES WITH DNA

Serum and Plasma

MeSH Terms

Conditions

Pancreatic Neoplasms

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsEndocrine Gland NeoplasmsDigestive System DiseasesPancreatic DiseasesEndocrine System Diseases

Study Officials

  • Diana Dickson

    Fujirebio Diagnostics, Inc.

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 24, 2014

First Posted

September 26, 2014

Study Start

May 1, 2014

Primary Completion

June 30, 2021

Study Completion

June 30, 2021

Last Updated

August 17, 2021

Record last verified: 2020-07

Locations