NCT02245971

Brief Summary

Endoscopic submucosal dissection (ESD) is an advanced technique that enables en bloc resection of superficial tumors in the gastrointestinal tract. ESD, however, is a time-consuming procedure that requires a high level of endoscopic skill to achieve a desirable oncologic outcome. Especially, ESD for the lesion which is located in the antrum of lesser curvature side is difficult. Because the antrum of lesser curvature side is dependent position, irrigated water and blood may prevent visual field of ESD. Generally, whole precutting around the lesion during the ESD is performed prior to dissection. However, it is expected that partial precutting method for the lesion located in the antrum of the lesser curvature may improve the visibility of ESD because it can help us the flap of the lesion evaginated easily. Therefore, we aimed to evaluate the procedure time of ESD for the lesion located in the antrum of the lesser curvature according to the precutting methods (whole precutting vs. partial precutting).

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jul 2013

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 26, 2013

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 12, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 12, 2014

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 15, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 22, 2014

Completed
Last Updated

January 16, 2019

Status Verified

January 1, 2019

Enrollment Period

1 year

First QC Date

September 15, 2014

Last Update Submit

January 14, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Procedure time

    Procedure time for the lesion located in the antrum of lesser curvature according to the precutting methods.

    Within 5 mins after the procedure

Secondary Outcomes (1)

  • En bloc resection rate

    Within 7 days after the procedure

Other Outcomes (1)

  • complete resection rate

    Within 7 days after the procedure

Study Arms (2)

Whole precutting group

ACTIVE COMPARATOR
Procedure: Whole precutting

Partial precutting group

ACTIVE COMPARATOR
Procedure: Partial precutting

Interventions

Partial precutting will be performed prior to dissection during the ESD.

Partial precutting group

Whole precutting will be performed prior to dissection during the ESD.

Whole precutting group

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Over 19 years old
  • Patients with gastric adenoma or early gastric cancer

You may not qualify if:

  • Patients who has undergone subtotal gastrectomy
  • Patients who has undergone gastrostomy
  • Patients with local recurred gastric adenoma or early gastric cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sevrance hospital

Seoul, 120-752, South Korea

Location

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2014

First Posted

September 22, 2014

Study Start

July 26, 2013

Primary Completion

August 12, 2014

Study Completion

August 12, 2014

Last Updated

January 16, 2019

Record last verified: 2019-01

Locations