Undifferentiated Connective Tissue Disease Registry
UCTD Registry
2 other identifiers
observational
100
1 country
1
Brief Summary
This registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tissue disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2012
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2012
CompletedFirst Submitted
Initial submission to the registry
September 3, 2014
CompletedFirst Posted
Study publicly available on registry
September 9, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 31, 2027
February 12, 2026
January 1, 2026
15.1 years
September 3, 2014
February 11, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Change in SF-36 Score
Patient questionnaire that measures health-related quality of life.
3 years
Change in Fatigue Severity Scale Score
Evaluates the impact of fatigue on the patient.
3 years
Change in Beck Depression Inventory Score
Self-reported depression severity questionnaire
3 years
Connective Tissue Disease Criteria
The physician will monitor which characteristics from each connective tissue disease the patient presents with. This will show how UCTD progresses and what the most prominent characteristics of the disease are.
3 years
Secondary Outcomes (4)
CBC
3 years
Comprehensive Metabolic Panel
3 years
Cholesterol Profile
3 years
Urinalysis
3 years
Study Arms (1)
Registry Participants
All patients who participate in the UCTD Registry will be put into this cohort and observed over approximately 3 years.
Interventions
There are no interventions associated with this registry as it is purely observational.
Eligibility Criteria
Patients under the care of any HSS rheumatologist that have been diagnosed with undifferentiated connective tissue disease.
You may qualify if:
- Any patient under the care of an HSS rheumatologist
- Positive ANA or a positive anti-ds DNA, anti-Ro/SS-A or other autoantibody on 2 or more occasions at least 12 weeks apart
- One or more signs or symptoms of connective tissue disease, including but not limited to arthralgia, arthritis, myalgia, rash, sicca symptoms, pericarditis, pleuritis, pulmonary symptoms, peripheral neuropathy, photosensitivity, alopecia, oral or nasal ulcers, leucopenia, anemia, and abnormal nailfold capillaroscopy
You may not qualify if:
- Patients who meet criteria for well defined CTD including SLE, rheumatoid arthritis, polymyositis or dermatomyositis, systemic sclerosis, or antiphospholipid syndrome
- Patients who are less than 18
- Those unable to give informed consent in English
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hospital for Special Surgery
New York, New York, 10021, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 3, 2014
First Posted
September 9, 2014
Study Start
March 1, 2012
Primary Completion (Estimated)
March 31, 2027
Study Completion (Estimated)
March 31, 2027
Last Updated
February 12, 2026
Record last verified: 2026-01