NCT02211092

Brief Summary

The purpose of this study is to develop an individually tailored home-based physical activity intervention for family caregivers of people with advanced cancer and assess the feasibility of a future randomized controlled trial (RCT) to test the effects of this intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2013

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

August 5, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 7, 2014

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
Last Updated

March 31, 2015

Status Verified

March 1, 2015

Enrollment Period

1.3 years

First QC Date

August 5, 2014

Last Update Submit

March 30, 2015

Conditions

Keywords

Family CaregiversAdvanced CancerPalliative CareSupportSelf CarePhysical Activity

Outcome Measures

Primary Outcomes (7)

  • Rate of recruitment

    Frequency counts of the number of participants recruited from each of the recruitment sites will be conducted and the overall rate of recruitment will be calculated. This criterion for advancing to a full RCT will be met if the estimated sample size required for a full RCT can likely be recruited in 2 years.

    9 months of running feasibility trial

  • Number of participants who drop out

    Frequency counts for the number of participants who drop out of both the experimental and control group will be conducted and the percentage rate of attrition in each group will be calculated. This criterion for advancing to a full RCT will be met if less than 30% of participants dropped out of the experimental or control group.

    9 months of running feasibility trial

  • Number of items complete on the outcome questionnaires

    To assess acceptability of outcome questionnaires and feasibility of data collection procedures for a full RCT, descriptive statistics (frequency counts) of complete versus incomplete items as well as the expected versus actual completion dates will be conducted at baseline, and week 6, 9, and 12 for both the experimental and control group on the following outcome measures: Positive and Negative Affect Schedule (PANAS); Lee Fatigue Scale (LFS); General Self-Rated Health question. This criterion for advancing to a full RCT will be met if less than 10% of items on each of the questionnaires are missing and less than 10% of participants are missing any one item on each of the questionnaires.

    Baseline, 6, 9, and 12 weeks

  • Rate of adherence to individual physical activity plans

    The number of weeks that participants were able to engage in physical activity levels at or above their retrospective baseline physical activity level in relation to the number of weeks that they were in the study will be calculated. Rate of adherence will be calculated for individual participants and the mean and median rate of adherence will be calculated for the experimental group. The proportion of participants that were able to engage in physical activity at or above their retrospective baseline level of physical activity 0-25%, 26-50%, 51-75%, and 76-100% of the time will be calculated. Qualitative data will also be collected and analyzed to explore what factors influence adherence to the individual physical activity plans. This criterion for advancing to a full RCT will be met if the rate of adherence to the individual PA plans is greater than or equal to 75%.

    12 weeks

  • Level of and change in physical activity levels

    The mean number of Metabolic Equivalent Task (MET) hours per week that participants engaged in physical activity as well as the number of minutes per week that participants engaged in light, moderate, and vigorous intensity PA for each of the experimental and control groups will be calculated.

    12 weeks

  • Level of adherence to physical activity intervention

    The number of weeks that each participant missed receiving the intervention will be calculated. In addition, qualitative data will be collected to assess the pattern of missed weeks for each participant including the reasons that any weeks were missed.

    12 weeks

  • Level of adherence to intervention delivery

    An intervention fidelity audit will be conducted. The percentage of audited participants that engaged in each of the main components of intervention delivery (i.e pre-baseline home visit, baseline home visit, and weekly telephone calls) will be calculated. In addition, the percentage of individual intervention delivery criteria items that were met in each component will be calculated for each audited participant.

    12 weeks

Secondary Outcomes (2)

  • Caregivers' perception of the acceptability of the intervention

    12 weeks

  • Caregivers' perception of benefits and/or risks of intervention

    12 weeks

Study Arms (2)

Physical activity intervention

EXPERIMENTAL

A 12 week individually tailored home-based physical activity program with goal-setting, a physical activity self-monitoring technique, and weekly telephone calls provided by the intervener for coaching and support.

Behavioral: Physical activity intervention

Usual care

OTHER

Access to usual community resources but no active lifestyle coaching.

Other: Usual care

Interventions

A 12 week individually tailored home-based physical activity program with goal-setting, a physical activity self-monitoring technique, and weekly telephone calls provided by the intervener for coaching and support.

Physical activity intervention

Access to usual community resources but no active lifestyle coaching.

Usual care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or older
  • able to speak and read English
  • involved in the care of a person with advanced cancer (stage III or IV) at home

You may not qualify if:

  • already participating in physical activity more than three days a week and 30 minutes or more per session as assessed by self-report
  • a current mental illness that has been treated with medication for \<8 weeks or that the caregiver intends to initiate medication for during the period of the intervention
  • any major physical health problem that would prevent caregivers from participating in the intervention as assessed by the Physical Activity Readiness Questionnaire (PAR-Q)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Jamie L Penner, RN, PhD(c)

    McGill University; Jewish General Hospital

    PRINCIPAL INVESTIGATOR
  • S Robin Cohen, PhD

    McGill University; Jewish General Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Nursing Doctoral Candidate

Study Record Dates

First Submitted

August 5, 2014

First Posted

August 7, 2014

Study Start

November 1, 2013

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

March 31, 2015

Record last verified: 2015-03

Locations