NCT02208895

Brief Summary

Pleural fluid glucose levels measured with bed-side point of care methods such as finger stick glucometers and I-STAT device correlate with the traditional in-lab testing methods.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2014

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 31, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 5, 2014

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 28, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 28, 2019

Completed
Last Updated

March 6, 2020

Status Verified

March 1, 2020

Enrollment Period

5.6 years

First QC Date

July 31, 2014

Last Update Submit

March 4, 2020

Conditions

Keywords

pleuralglucoseglucometeri-STAT

Outcome Measures

Primary Outcomes (1)

  • Correlation of pleural fluid glucose measured with a glucometer and the I-STAT with the pleural fluid glucose level measured in the Lab

    Primary outcome will be the inter-assay precision of the finger stick glucometer and the I-STAT device as compared to the Gold standard in lab testing of pleural glucose.This will be done using the Bland-Altman plot.

    <1 hour

Secondary Outcomes (1)

  • Intra assay precision of pleural fluid glucose measured with a glucometer and with an I-STAT device.

    < 1hour

Study Arms (1)

iSTAT Study Group

Measure glucose of pleural fluid via glucometer, in the laboratory, and using the iSTAT device to see if the three methods give a similar reading or not.

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Pleural effusions

You may qualify if:

  • any patient 18 to 99 year old with a diagnosis of pleural effusion and undergoing a diagnostic thoracentesis.

You may not qualify if:

  • Inability to provide informed consent by the patient or the surrogate to enroll for the planned study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VAMC OKC

Oklahoma City, Oklahoma, 73104, United States

Location

Biospecimen

Retention: NONE RETAINED

Pleural fluid

MeSH Terms

Conditions

Pleural Effusion

Condition Hierarchy (Ancestors)

Pleural DiseasesRespiratory Tract Diseases

Study Officials

  • Houssein Youness, MD

    OUHSC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 31, 2014

First Posted

August 5, 2014

Study Start

February 1, 2014

Primary Completion

August 28, 2019

Study Completion

August 28, 2019

Last Updated

March 6, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Deidentified data may only be shared upon review of OUHSC Legal office and IRB. Data sharing agreement required. Contact research@ouhsc.edu to initiate data requests. No personally identifiable data will be shared.

Locations