NCT02203734

Brief Summary

This project will investigate the effects of massage therapy on depressed pregnant women. The investigators expect that massage therapy will improve blood flow from the mother to the fetus and reduce prematurity and depression.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable pregnancy

Timeline
Completed

Started Feb 2012

Longer than P75 for not_applicable pregnancy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2012

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

November 28, 2013

Completed
8 months until next milestone

First Posted

Study publicly available on registry

July 30, 2014

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

October 9, 2015

Status Verified

October 1, 2015

Enrollment Period

3.6 years

First QC Date

November 28, 2013

Last Update Submit

October 8, 2015

Conditions

Keywords

PregnancyDepressionMassage

Outcome Measures

Primary Outcomes (1)

  • Change Doppler Ultrasound

    Change in Doppler Ultrasound to assess Uterine Artery Resistance Index values

    First Day of Study and 10 Weeks After

Secondary Outcomes (3)

  • Change in CES-D

    First Day of Study and 10 Weeks After

  • Change Saliva Samples

    First Day of Study and 10 Weeks After

  • Birth Outcome Data

    Birth

Study Arms (2)

Moderate Pressure Massage

EXPERIMENTAL

Moderate Pressure Massage Therapy

Procedure: Moderate Pressure Massage

Light Pressure Massage

SHAM COMPARATOR

Light Pressure Massage Therapy

Procedure: Light Pressure Massage

Interventions

The massage therapy will begin with the mother in a side-lying position, with pillows positioned behind her back and between her legs for support. The massage is given in the following sequence and repeated twice (10 minutes on each side for 20 minutes total) on the following areas: 1) Head and neck: 2) Back: 3) Arms: and 4) Legs. The effective moderate pressure (measured by a pressure meter) is 8 db or a slight indentation in the skin.

Moderate Pressure Massage

The light pressure massage group will receive light pressure massage in contrast to the treatment group who will receive moderate pressure massage. As with moderate pressure massage, each session will begin with the mother in a side-lying position, with pillows positioned behind her back and between her legs for support. The massage is given in the following sequence and repeated twice (10 minutes on each side for 20 minutes total) on the following areas: 1) Head and neck: 2) Back: 3) Arms: and 4) Legs.

Light Pressure Massage

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Uncomplicated singleton pregnancy
  • Depression
  • \< 20 weeks GA at recruitment

You may not qualify if:

  • Pregnancy complications
  • HIV
  • Smoking, drug use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Miami

Miami, Florida, 33136, United States

Location

Related Links

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Research Associate Professor

Study Record Dates

First Submitted

November 28, 2013

First Posted

July 30, 2014

Study Start

February 1, 2012

Primary Completion

September 1, 2015

Study Completion

September 1, 2015

Last Updated

October 9, 2015

Record last verified: 2015-10

Locations