NCT02190461

Brief Summary

Open clinical trial with 1 year follow up comparing the impact of an Early Respiratory Rehabilitation program with the conventional Respiratory Rehabilitation in COPD re-admitted patients. Outcomes will be exacerbations, symptoms, functional capacity and quality of life related to health (HRQOL).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
39

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2013

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

July 11, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 15, 2014

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 9, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 9, 2017

Completed
Last Updated

September 6, 2018

Status Verified

September 1, 2018

Enrollment Period

4.2 years

First QC Date

July 11, 2014

Last Update Submit

September 4, 2018

Conditions

Keywords

Early Respiratory RehabilitationChronic Obstructive Pulmonary DiseaseRe-admitted patientsOpen clinical trialExacerbations

Outcome Measures

Primary Outcomes (1)

  • Exacerbations

    Exacerbations with or without admission due to respiratory illness

    1 year

Secondary Outcomes (3)

  • Dyspnea

    1 year

  • Functional capacity

    1 year

  • Quality of life related to health

    1 year

Study Arms (2)

Early Respiratory Rehabilitation

EXPERIMENTAL

Starting the Early Respiratory Rehabilitation programme during the admission and continues it at home immediately after discharge for a period of 3 months.

Procedure: Early Respiratory Rehabilitation Program

Conventional Respiratory Rehabilitation

ACTIVE COMPARATOR

Started a conventional Respiratory Rehabilitation programme at home one month after discharge from hospital and continues for 3 months.

Procedure: Conventional Respiratory Rehabilitation Program

Interventions

Early Respiratory Rehabilitation
Conventional Respiratory Rehabilitation

Eligibility Criteria

Age41 Years - 110 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age\> 40 years
  • Diagnostic criteria of COPD GOLD II-IV confirmed by spirometry
  • Having frequent re-admissions (≥ 2 times / year).
  • Sign the informed consent.

You may not qualify if:

  • Have completed a pulmonary rehabilitation program (including training) in the last 6 months.
  • Respiratory and / or cardiac serious associated diseases.
  • End-stage COPD (inability to perform exercises or treatment with morphine).
  • Prognosis of \<6 months.
  • Living in a residence or not having a primary caregiver.
  • Cognitive disorders that prevent active participation.
  • Patients who are admired to other hospitalization rooms than Pneumology.
  • Patients who do not belong to the area of health coverage of the Respiratory Rehabilitation home team

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Servicio de Neumología Hospital de la Santa Creu i Sant Pau

Barcelona, 08025, Spain

Location

Related Publications (1)

  • Guell-Rous MR, Morante-Velez F, Flotats-Farre G, Paz-Del Rio LD, Closa-Rusines C, Ouchi-Vernet D, Segura-Medina M, Bolibar-Ribas I. Timing of Pulmonary Rehabilitation in Readmitted Patients with Severe Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. COPD. 2021 Feb;18(1):26-34. doi: 10.1080/15412555.2020.1856059. Epub 2020 Dec 7.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Fátima E Morante, Nurse

    Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 11, 2014

First Posted

July 15, 2014

Study Start

April 1, 2013

Primary Completion

June 9, 2017

Study Completion

June 9, 2017

Last Updated

September 6, 2018

Record last verified: 2018-09

Locations