NCT02189876

Brief Summary

The FemAALES Project is a community collaborative two-arm intervention designed to prevent HIV (human immunodeficiency) and STD (sexually transmitted disease) infection and transmission among African American women and men by reducing sexual risk factors and enhancing sexual negotiation skills. The team of investigators is a collaboration of researchers and community service providers who are committed to developing prevention interventions that employ holistic and culturally relevant approaches. This includes recognizing the impact of forces such as racism, sexism, and gender expectations on individual behavior and relationship dynamics in African American communities. Specifically, the investigators hypothesis is that compared to the control condition the FemAALES intervention arm will reduce risky sexual behavior and STI (sexually transmitted infection) incidence and will increase condom self-efficacy and risk behavior communication with sexual partners.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
256

participants targeted

Target at P50-P75 for not_applicable hiv

Timeline
Completed

Started Jul 2013

Longer than P75 for not_applicable hiv

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

June 11, 2014

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 15, 2014

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2018

Completed
Last Updated

August 3, 2018

Status Verified

August 1, 2018

Enrollment Period

4.8 years

First QC Date

June 11, 2014

Last Update Submit

August 1, 2018

Conditions

Keywords

HIV PreventionBehavioral InterventionCondom UseAfrican AmericanSexually Transmitted DiseaseSexually Transmitted InfectionInternet

Outcome Measures

Primary Outcomes (3)

  • Change in number of sex partners from baseline

    Determine the impact of the FemAALES intervention compared to the control condition on the number of vaginal and anal sex partners in the prior 90 days .

    3 and 9 months

  • Change in frequency of unprotected sex from baseline.

    Determine the impact of the FemAALES interventions compared to the control condition on the number of vaginal or anal sex acts reported without condoms in the prior 90 days.

    3 and 9 months

  • Change in bacterial STDs from baseline

    Examine the impact of the FemAALES interventions compared to the control condition on the incidence of gonorrhea and chlamydia.

    9 months

Secondary Outcomes (1)

  • Change in Safer Sex Negotiation Skills and Behaviors

    3 and 9 months

Other Outcomes (1)

  • Intervention Effect on Use of New Media

    9 months

Study Arms (2)

FemAALES

EXPERIMENTAL

Females of African American Legacy Empowering Self Intervention. A nine session, theoretically grounded small group intervention.

Behavioral: Standard of CareBehavioral: FemAALES

Standard of Care

ACTIVE COMPARATOR

A one-time STD/family planning testing and counseling session provided to all study participants.

Behavioral: Standard of Care

Interventions

All participants will be provided a STD/HIV pre-test counseling session. This session will be provided by either certified project staff or clinical staff at a Los Angeles clinic that conduct State of CA Fam Pact services for patients who are of child bearing age, including our current study partner St. John's Well Child and Family Center and our former study partner, JWCH (John Wesley Community Health) Institute-Wesley Health Center Clinics. Following the counseling session, the participant will be asked to provide a sample of urine to test for Chlamydia and Gonorrhea.

FemAALESStandard of Care
FemAALESBEHAVIORAL

Women will attend 9 small group sessions over 4 weeks. Three of these sessions will focus specifically on participants learning to use a computer, set up an email account, communicate with the team and the group using the Internet, and developing a prevention message for display on project website and social media accounts. The other 6 sessions will include discussions on the following topics: being a Black woman in American, Black history, assessing personal health, changing current behaviors, HIV/AIDS information, and education, self-empowerment, communication skills, reasons to change, and goal setting.

FemAALES

Eligibility Criteria

Age18 Years - 54 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • female sex
  • self-identifies as Black/African American
  • years of age or older
  • English speaking
  • has had unprotected vaginal or anal sex in the last 90 days
  • any male partner in the last 90 days has done one or more of the following: had sex with a man; had sex with a male-to-female transgender; used crack cocaine, heroin, or methamphetamines; been incarcerated for more than 6 months; had sex with other female partners during the relationship; OR - a male partner in the last 90 days has an unknown sexual history
  • publicly funded or public subsidized health insurance

You may not qualify if:

  • participated in a small group HIV prevention program in the past 12 months, participated in HARRP program in the past 12 months, has private insurance, refuses chlamydia or gonorrhea test at baseline,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

St. John's Well Child and Family Center

Los Angeles, California, 90037, United States

Location

Charles Drew University of Medicine and Science

Los Angeles, California, 90059, United States

Location

Related Publications (1)

  • Adeyeba MO, Montazeri Q, Bivens-Davis T, Schrode KM, Harawa NT. Reducing Human Immunodeficiency Virus and Sexually Transmitted Infections Risk in African American Women with At-Risk Male Partners: A Randomized Trial. J Womens Health (Larchmt). 2023 Mar;32(3):311-322. doi: 10.1089/jwh.2022.0194. Epub 2022 Dec 14.

MeSH Terms

Conditions

Sexually Transmitted Diseases

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Communicable DiseasesInfectionsGenital DiseasesUrogenital DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Officials

  • Nina T Harawa, Ph.D, MPH

    Charles Drew University

    PRINCIPAL INVESTIGATOR
  • Martin Shapiro, MD Ph.D MPH

    University of California, Los Angeles

    PRINCIPAL INVESTIGATOR
  • Samuel Gonzalez, MS

    St. John's Well Child and Family Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 11, 2014

First Posted

July 15, 2014

Study Start

July 1, 2013

Primary Completion

April 1, 2018

Study Completion

April 1, 2018

Last Updated

August 3, 2018

Record last verified: 2018-08

Locations