NCT02189291

Brief Summary

Objectives The objective of this study is to help identify the best practice regarding the use of indwelling catheter after minimally invasive urogynecologic surgery. Investigators propose a randomized controlled trial comparing the immediate removal of indwelling urethral catheter, after minimally invasive sacrocolpopexy, to the present standard catheter removal on post operative day one. Evidence based catheter management will be helpful to both providers and patients in post-operative decision making. Specific Aims Aim 1: To demonstrate that immediate removal of catheter after minimally invasive sacrocolpopexy results in shorter hospital stay than removal on postoperative day 1. Aim 2: To demonstrate that immediate removal of catheter after minimally invasive sacrocolpopexy confers no increased risk of re-catheterization. Aim 3: To demonstrate that immediate removal of catheter after minimally invasive sacrocolpopexy decreases the occurrence of urinary tract infection. Design A randomized controlled trial comparing the standard overnight indwelling urethral catheterization with removal of catheter immediately post surgery after minimally invasive sacrocolpopexy, at Oregon Health \& Science University. Outcome measures Primary outcome measures are hospital stay in hours after completion of surgery and need for re-catheterization. Hospital stay will be counted from the time the patient leaves the operating room to the time she leaves the hospital. To avoid confounding, investigators are only including the first / morning case of the day. For re-catheterization, investigators will evaluate if patient was able to void after completion of surgery. Investigators will compare the post voiding residuals, the need for re-catheterizations and the numbers of patients going home with an indwelling catheter between the two groups. Investigators will also compare the number of urinary tract infections, as documented by urine culture and subsequent treatment, between the two groups. Study Subjects Study subjects will be women undergoing minimally invasive sacrocolpopexy. Women will be invited to participate in the study during their preoperative visit. If they agree to participation, this will be noted in their chart. Randomization to group will occur immediately following surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2014

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

July 3, 2014

Completed
11 days until next milestone

First Posted

Study publicly available on registry

July 14, 2014

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2018

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2018

Completed
Last Updated

March 15, 2019

Status Verified

March 1, 2019

Enrollment Period

4 years

First QC Date

July 3, 2014

Last Update Submit

March 13, 2019

Conditions

Keywords

Indwelling catheterHospital stayUrinary tract infectionSacrocolpopexy

Outcome Measures

Primary Outcomes (1)

  • Hospital stay

    Primary outcome measure is hospital stay in hours after completion of surgery. Hospital stay will be counted from the time the patient leaves the operating room to the time she leaves the hospital.

    4 weeks

Secondary Outcomes (2)

  • Re-catheterization

    Upto 4 weeks

  • Urinary tract infection

    upto 4 weeks

Study Arms (2)

Immediate catheter removal

EXPERIMENTAL

The indwelling Foley catheter will be removed prior to exiting the operating room.

Procedure: Immediate catheter removal

Post op day 1 catheter removal

ACTIVE COMPARATOR

Patients assigned to this group will follow the standard of care at present, with removal of indwelling catheter on the morning of postoperative day 1.

Procedure: Post op day 1 catheter removal

Interventions

The indwelling catheter will be removed prior to exiting the operating room.

Immediate catheter removal

For patients assigned to catheter removal on post operative day one, which is the standard of care at this point.

Post op day 1 catheter removal

Eligibility Criteria

Age21 Years - 85 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women undergoing minimally invasive sacrocolpopexy
  • Sacrocolpopexy with or without concomitant procedures
  • Patients having the first start surgery of the day to standardize hospital time.

You may not qualify if:

  • Elevated post void residual (PVR)
  • Mobility problems
  • Neurological conditions
  • Intra-operative cystotomy or urinary tract injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

St John Hospital & Medical Center

Detroit, Michigan, 48236, United States

Location

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location

Legacy Good Samaritan Medical Center

Portland, Oregon, United States

Location

Related Publications (2)

  • Ellahi A, Stewart F, Kidd EA, Griffiths R, Fernandez R, Omar MI. Strategies for the removal of short-term indwelling urethral catheters in adults. Cochrane Database Syst Rev. 2021 Jun 29;6(6):CD004011. doi: 10.1002/14651858.CD004011.pub4.

  • Aslam MF, Bazzi AA, Hagglund KH, Osmundsen BC. When to Remove the Indwelling Catheter After Minimally Invasive Sacrocolpopexy? CARESS (CAtheter REmoval after Sacrocolpopexy Surgery). Female Pelvic Med Reconstr Surg. 2020 Feb;26(2):120-127. doi: 10.1097/SPV.0000000000000826.

MeSH Terms

Conditions

Pelvic Organ ProlapseUrinary Tract InfectionsUrinary Retention

Condition Hierarchy (Ancestors)

ProlapsePathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsInfectionsUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesUrination Disorders

Study Officials

  • Muhammad F Aslam, MD

    St. John Hospital & Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

July 3, 2014

First Posted

July 14, 2014

Study Start

July 1, 2014

Primary Completion

July 1, 2018

Study Completion

December 31, 2018

Last Updated

March 15, 2019

Record last verified: 2019-03

Locations