NCT02186288

Brief Summary

Effect of High-flow nasal cannula oxygen on end-expiratory lung volumes determined by electrical impedance tomography

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jul 2014

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 20, 2014

Completed
11 days until next milestone

Study Start

First participant enrolled

July 1, 2014

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 10, 2014

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2014

Completed
Last Updated

July 24, 2015

Status Verified

July 1, 2015

Enrollment Period

3 months

First QC Date

June 20, 2014

Last Update Submit

July 23, 2015

Conditions

Critical CareHigh-flow Nasal Cannula OxygenElectrical Impedance TomographyEnd Expiratory Lung VolumeEnd Expiratory Lung ImpedanceDiaphragmatic Ultrasound

Keywords

Critical CareHigh-flow nasal cannula oxygenElectrical impedance tomographyEnd expiratory lung volumeEnd expiratory lung impedanceDiaphragmatic ultrasound

Outcome Measures

Primary Outcomes (3)

  • End-expiratory lung volume (EELV) determined by electrical impedance tomography before NIV non invasive ventilation

    at day 1

  • End-expiratory lung volume (EELV) determined by electrical impedance tomography during NIV non invasive ventilation

    at day 1

  • End-expiratory lung volume (EELV) determined by electrical impedance tomography after NIV non invasive ventilation

    at day 1

Secondary Outcomes (3)

  • Anterior, medio-anterior, medio-posterior and posterior EELV at each time

    at day 1

  • Diaphragmatic excursion and thickness determined by ultrasound

    at day 1

  • Ventilatory frequency

    at day 1

Study Arms (1)

Adult ICU patients

Other: High-flow nasal cannula oxygen

Interventions

High-flow nasal cannula oxygenOTHER
Adult ICU patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult ICU patients

You may qualify if:

  • Adult ICU patients requiring High-flow nasal cannula oxygen
  • Consent of patients or family
  • Arterial line

You may not qualify if:

  • Tracheotomized patients
  • Dressings in the thoracic area

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

Location

Study Officials

  • Sébastien PERBET

    University Hospital, Clermont-Ferrand

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 20, 2014

First Posted

July 10, 2014

Study Start

July 1, 2014

Primary Completion

October 1, 2014

Study Completion

October 1, 2014

Last Updated

July 24, 2015

Record last verified: 2015-07

Locations

FR(1)