Pre-dinner vs. Post-dinner Exercise on Glycemic Control
Exercise Timing and Postprandial Glycemia in Type 2 Diabetes
1 other identifier
interventional
13
0 countries
N/A
Brief Summary
With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable type-2-diabetes
Started Sep 2013
Shorter than P25 for not_applicable type-2-diabetes
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2014
CompletedFirst Submitted
Initial submission to the registry
June 30, 2014
CompletedFirst Posted
Study publicly available on registry
July 2, 2014
CompletedJune 8, 2017
June 1, 2017
7 months
June 30, 2014
June 6, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
glucose concentrations
Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Secondary Outcomes (1)
triglyceride concentrations
Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Other Outcomes (1)
GLP-1 concentrations
Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Study Arms (3)
No exercise
EXPERIMENTALparticipants will remain sedentary during testing
Meal then exercise
EXPERIMENTAL45 min of resistance training will be performed after a standard meal
exercise then meal
EXPERIMENTAL45 min of resistance training will be performed prior to a standard meal
Interventions
During the no exercise trial (NoEX), the participants will remain sedentary during testing.
During the post-meal exercise trial (M→EX), 45 min of resistance training will be performed
During the exercise prior to the meal trial (EX→M), 45 min of resistance training will be performed
Eligibility Criteria
You may qualify if:
- Obese ( body mass index 30-45 kg/m2)
- Physician diagnosed with type 2 diabetes receiving standard medical care
- Non-smokers
- Pregnancy
- Lactating mothers
You may not qualify if:
- Insulin
- Surgical weight loss
- Orthopedic limitations to exercise
- Weight loss in the previous 3 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Heden TD, Liu Y, Kanaley JA. A comparison of adipose tissue interstitial glucose and venous blood glucose during postprandial resistance exercise in patients with type 2 diabetes. J Appl Physiol (1985). 2018 Apr 1;124(4):1054-1061. doi: 10.1152/japplphysiol.00475.2017. Epub 2017 Sep 28.
PMID: 28970202DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- professor
Study Record Dates
First Submitted
June 30, 2014
First Posted
July 2, 2014
Study Start
September 1, 2013
Primary Completion
April 1, 2014
Study Completion
April 1, 2014
Last Updated
June 8, 2017
Record last verified: 2017-06
Data Sharing
- IPD Sharing
- Will not share