NCT02179684

Brief Summary

The purpose of this study is to investigate if an early surgical intervention on patienst with Bell´s Palsy has a better impact on their facial muscular function and their quality of life as compared to conventional therapy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 30, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 2, 2014

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2018

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2019

Completed
Last Updated

July 2, 2014

Status Verified

June 1, 2014

Enrollment Period

4.3 years

First QC Date

June 30, 2014

Last Update Submit

June 30, 2014

Conditions

Keywords

Cranial Nerve fascial paresis

Outcome Measures

Primary Outcomes (1)

  • Sunny Brook (SB) score > 70

    Patients with Bell´s Palsy that has been randomized to conventional treatment or early surgical intervention are scored according to SB after 12 month of study participation.

    1 year

Secondary Outcomes (2)

  • Facial Disability Index

    15 month

  • FaCe

    15 month

Study Arms (2)

Early surgery

EXPERIMENTAL

Patienst with Bell´s Palsy with an early surgical intervention (\< 3month), according to 'baby-sitter' method

Procedure: Baby-sitter surgery N. fascialis

Conventional treatment and follow-up

ACTIVE COMPARATOR

Patienst with Bell´s Palsy treated with conventional treatment and standardized physiotherapy according to Jaqueline Diels model.

Other: Conventional treatment and follow-up

Interventions

Early surgery

Patient´s with Bells´palasy are treated with conventional treatment and follow-up

Conventional treatment and follow-up

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with Bell´s Palsy
  • Men and women aged 18-55 y
  • Score \< 70 according to Sunny Brook scale (SB)
  • Signed informed consent

You may not qualify if:

  • High bloodpressure
  • Diabetes
  • Pregnancy
  • Currently on immunodepressive treatment
  • Smoker
  • Psychiatric disorder
  • Cor incomp, according to NYHA grade: IV, kidney or liver disorder, that greatly influence patienst ability to receive surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Karolinska University Hospital

Stockholm, Solna, SE-17176, Sweden

Location

Uppsala Akademiska Hospital, EENT department

Uppsala, Uppsala County, SE-751 85, Sweden

Location

MeSH Terms

Conditions

Bell Palsy

Condition Hierarchy (Ancestors)

Herpesviridae InfectionsDNA Virus InfectionsVirus DiseasesInfectionsMouth DiseasesStomatognathic DiseasesFacial Nerve DiseasesCranial Nerve DiseasesNervous System Diseases

Study Officials

  • Malou Hultcrantz, M.D prof.

    Karolinska Institutet

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D. Professor

Study Record Dates

First Submitted

June 30, 2014

First Posted

July 2, 2014

Study Start

November 1, 2013

Primary Completion

February 1, 2018

Study Completion

November 1, 2019

Last Updated

July 2, 2014

Record last verified: 2014-06

Locations