Feasibility of Using Ultrasound to Track Respiration Motion
1 other identifier
observational
15
1 country
1
Brief Summary
The purpose of this study is to evaluate the effectiveness of using ultrasound to image and track pancreas/duodenum motion during radiation therapy treatment delivery. Also develop a workflow and process to allow the final ultrasound system to be used routinely by radiation therapists.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Feb 2014
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2014
CompletedFirst Submitted
Initial submission to the registry
June 17, 2014
CompletedFirst Posted
Study publicly available on registry
June 25, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2020
CompletedOctober 12, 2022
October 1, 2022
6.8 years
June 17, 2014
October 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Evaluate the use of ultrasound to detect motion of pancrease and surrounding structures
Design and construct stands to hold the ultrasound probe. Issues to be considered in the design include (i) avoiding the stand and probe blocking radiation beams, (ii) avoiding ultrasound going through the ribs, (iii) minimizing the effect of respiration motion. Explore building the probe into the immobilization device (e.g., Alpha cradle) or using robotic arm.
5 years from the date of enrollment
Secondary Outcomes (1)
Quality of ultrasound imaging for Pancreas
3 years from the date of enrollment
Other Outcomes (1)
Assess organ motion and compare in conjunction with magnetic resonance imaging or CT
5 years from the date of enrollment
Study Arms (1)
Pancreas cancer
Develope a stand, cradle or robotic arm to hold the ultrasound probe, to obtain an ultrasound just before a standard radiation therapy treatment is given.
Interventions
Ultrasound to be done just before standard radiation therapy treatment
Eligibility Criteria
Patients who will receive standard radiation therapy for pancreas cancer.
You may qualify if:
- Patients who will receive standard radiation therapy for pancreas cancer
You may not qualify if:
- Patients who will receive standard radiation therapy for sites other than pancreas cancer
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Froedtert Hospital & the Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
Related Publications (1)
Li XA, Qi XS, Pitterle M, Kalakota K, Mueller K, Erickson BA, Wang D, Schultz CJ, Firat SY, Wilson JF. Interfractional variations in patient setup and anatomic change assessed by daily computed tomography. Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):581-91. doi: 10.1016/j.ijrobp.2006.12.024. Epub 2007 Feb 27.
PMID: 17331669BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
An Tai, PhD
Medical College of Wisconsin
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
June 17, 2014
First Posted
June 25, 2014
Study Start
February 1, 2014
Primary Completion
November 1, 2020
Study Completion
November 1, 2020
Last Updated
October 12, 2022
Record last verified: 2022-10
Data Sharing
- IPD Sharing
- Will not share