Multivariate Analysis of Serum High Sensitivity C-Reactive Protein in Patients With Acute Phase Stroke

NCT02171858 | Unknown DMC

• 1 other identifier: CRP-S1
• Study Type: observational
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is one of main causes of death and impairment worldwide. Objective of this study is to analyze serum High Sensitivity C-Reactive Protein in acute phase stroke in patients attended at Petróleos Mexicanos Hospital Central Sur de Alta Especialidad and to correlate with stroke extension and clinical features.

Conditions

Stroke; National Institutes of Health Stroke Scale; Serum High Sensitivity C-Reactive Protein

Keywords

Stroke; National Institutes of Health Stroke Scale; Serum high sensitivity C-Reactive Protein

Outcome Measures

Primary Outcomes (1)

• Measure of serum High sensitivity C-Reactive Protein level

  Serum levels of serum High sensitivity C-Reactive Protein will be measured in patients with suspicion of stroke at the emergency room within the first 8 hours of arrival at our hospital

  within the first 8 hours since admission to hospital

Secondary Outcomes (1)

• National Institutes of Health Stroke Scale

  within the first 4 hours since admission to emergency room

Other Outcomes (3)

• Stroke extension

  within the first 4 hours since admission to emergency room

• Origin of stroke

  origin will be diagnosed during the hospital stay expecting no more than 1 week

• Hospital stay

  hospital stay is expected for no more than 1 week unless intensive care unit is needed

Study Arms (1)

stroke

Patients admitted to hospital who are diagnosed with stroke will be treated as usually a our center by observation, venous or arterial thrombolysis depending on extension, condition, thrombolysis feasibility.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients affiliated to Petróleos Mexicanos medical system of any gender between 18 and 80 years old suspected of acute phase stroke who arrive to emergency room at our hospital

You may qualify if:

• Patients suspected of acute phase stroke who arrive to emergency room at our hospital
• Patients affiliated to Petróleos Mexicanos medical system
• Patients of any gender
• Patients between 18 and 80 years old

You may not qualify if:

• Stroke provoked by angiographic procedure
• Pregnancy
• Patient under chemotherapy or radiotherapy
• Recently surgery or trauma among last 30 days
• Heparin usage
• Stroke and/ or thrombolysis history
• Active infection
• Liver disease

Sponsors & Collaborators

• Hospital Central Sur de Alta Especialidad: lead

Study Sites (1)

Hospital Central Sur Alta Especialidad

Mexico City, Tlalpan, 14140, Mexico

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

serum

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Md

Study Record Dates

• First Submitted: June 4, 2014
• First Posted: June 24, 2014
• Study Start: June 1, 2013
• Primary Completion: January 1, 2015
• Last Updated: June 24, 2014

Record last verified: 2014-06

Locations

ME (1)