Inferior Vena cavaCollapsibility Index in Patients With Acute Kidney Injury

NCT02165072 | Completed Results

• 1 other identifier: L14-052
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This is an observational study that will examine the possibility of determining the type of Acute Kidney Injury (AKI) using bedside ultrasound machines.

Conditions

Acute Kidney Injury

Keywords

Inferior vena cava; Kidney injury; Ultrasound

Outcome Measures

Primary Outcomes (2)

• Maximum and Minimum Diameters of the Inferior Vena Cava in Patients With Acute Kidney Injury

  The investigators will measure the maximum and minimum diameters of the inferior vena cava with patients with acute kidney injury.

  Day 1 of ICU admission

• Percent Collapse of the Inferior Vena Cava in Patients With Acute Kidney Injury

  The investigators will measure the maximum and minimum diameters of the inferior vena cava with patients with acute kidney injury and calculate the percent change between the maximum and minimum diameters.

  Day 1 of ICU admission

Eligibility Criteria

• Age: 18 Years - 89 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects ages 18-89 years with AKI (creatinine of 1.7mg/100ml or higher for less than 24 hours from baseline creatinine ≤1.2 or with unknown baseline creatinine). Standard of care treatment will not be different for patients taking part in this study. Participants will have bedside ultrasounds on days 0, 1, and 3, and baseline and follow-up data will be collected from medical records.

You may qualify if:

• Creatinine of 1.7 mg/100ml or higher for less than 24 hours from baseline creatinine ≤1.2 or with unknown baseline creatinine
• Age range: 18-89 years
• Age range ≥ 18

You may not qualify if:

• \. Only chronic renal disease will exclude a patient from our study regardless of past medical history and medications they are taking. (For the purposes of this study, any patient with creatinine higher than 1.2 mg /100ml for more than 24 hours will be identified as having chronic renal disease.)

Sponsors & Collaborators

• Texas Tech University Health Sciences Center: lead

Study Sites (1)

Texas Tech Univrsity Health Science Center

Lubbock, Texas, 79430, United States

Location

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Limitations and Caveats

This study is straightforward and involves measurements of the inferior vena cava. The study population was heterogeneous. Study measurements depend on the ability to identify the inferior vena cava with precision and make accurate measurements.

Results Point of Contact

• Title: Dr Kenneth Nugent
• Organization: Texas Tech university Health Sciences Center, Lubbock, TX

Kenneth.nugent@ttuhsc.edu

(806) 743-6847

Study Officials

• Kenneth M Nugent, MD

  Texas Tech University Health Sciences Center

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 13, 2014
• First Posted: June 17, 2014
• Study Start: February 1, 2014
• Primary Completion: October 1, 2015
• Study Completion: October 1, 2015
• Last Updated: June 23, 2016
• Results First Posted: June 23, 2016

Record last verified: 2016-06

Locations

US (1)