NCT02163798

Brief Summary

Cardiovascular diseases (CVD) accounted for major mortality and morbidity rates in Hong Kong (HK) other than cancer. Increasing energy expenditure through regular exercise participation has been found to lower the risk of CVD such as hyperlipidemia and obesity. Healthcare professionals often prescribe lifestyle exercises for disease prevention, rehabilitation, and health maintenance purposes. Previous study revealed that Tai Chi and walking were widely practice by HK citizens. However, limited studies are found to compare the health benefits between Tai Chi and walking. Do Tai Chi and walking have equally effective in raising metabolic rate and reducing CVD risks? The difference in energy cost between a single bout of Tai Chi and walking has not been documented. Limited studies report the effects of Tai Chi in lowering the CVD risk. Since walking and Tai Chi are being heavily promoted in HK in recent years, there is an urgent need to document the evidence of these two common forms of exercise in terms of reducing CVD risks. Therefore, the purpose of the present study was to investigate the energy costs as well as CV health benefits, in terms of aerobic fitness, body composition, blood pressure, and blood lipid profiles, from the walking and Tai Chi exercise in a sample of HK Chinese adults, and to compare the effects between these two exercises. The investigators hypothesized that Tai Chi and walking had similar effects on improving energy cost and reducing CVD risks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
374

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2005

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2006

Completed
7.9 years until next milestone

First Submitted

Initial submission to the registry

June 10, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 16, 2014

Completed
Last Updated

August 20, 2014

Status Verified

August 1, 2014

Enrollment Period

1.6 years

First QC Date

June 10, 2014

Last Update Submit

August 19, 2014

Conditions

Keywords

Tai ChiWalkingPhysical activityRandomized controlled trialChinese populationExerciseBody compositionCardiovascular risk factorEnergy expenditureFitnessSF-12

Outcome Measures

Primary Outcomes (4)

  • Changes of aerobic fitness after intervention

    The aerobic fitness, in terms of maximal oxygen intake (VO2max in ml/min/kg), was measured at baseline (pre-intervention) and 3 months (post-intervention), respectively. The pre-intervention VO2max minus the post-intervention VO2max was the "Changes of aerobic fitness after intervention"

    Measures were done at two time points: baseline and 3 months

  • Changes of resting VO2 (ml/min/kg) after intervention

    Resting VO2 (ml/min/kg) was an indicator of resting energy expenditure (REE) in our study. It was measured at baseline (pre-intervention) and 3 months (post-intervention), respectively. The pre-intervention REE-VO2 minus the post-intervention REE-VO2 was the "Changes of resting VO2 after intervention"

    Measures were done at two time points: baseline and 3 months

  • Changes of body mass index (BMI) after intervention

    BMI was an indicator of body composition in our study. It was measured at baseline (pre-intervention) and 3 months (post-intervention), respectively. The pre-intervention BMI minus the post-intervention BMI was the "Changes of BMI after intervention"

    Measures were done at two time points: baseline and 3 months

  • Changes of waist circumference (WC) after intervention

    WC was an indicator of body composition in our study. It was measured at baseline (pre-intervention) and 3 months (post-intervention), respectively. The pre-intervention WC minus the post-intervention WC was the "Changes of WC after intervention"

    Measures were done at two time points: baseline and 3 months

Secondary Outcomes (23)

  • Changes of resting heart rate (HR in beats/min) after intervention

    Measures were done at two time points: baseline and 3 months

  • Changes of resting kilocalorie expenditure (KCal in KCal/min) after intervention

    Measures were done at two time points: baseline and 3 months

  • Changes of hip circumference (HC) after intervention

    Measures were done at two time points: baseline and 3 months

  • Changes of waist hip ratio (WHR) after intervention

    Measures were done at two time points: baseline and 3 months

  • Changes of body fat percentage after intervention

    Measures were done at two time points: baseline and 3 months

  • +18 more secondary outcomes

Study Arms (3)

Tai Chi Group

EXPERIMENTAL

Participants in this group received a 12-week instructor-led Tai Chi training program.

Behavioral: 12-week instructor-led Tai Chi training program

Walking Group

EXPERIMENTAL

Participants in this group received a 12-week instructor-led brisk walking training program.

Behavioral: 12-week instructor-led brisk walking training program

Control Group

NO INTERVENTION

Participants in the control group did not receive intervention during the 12 weeks, and were told that they would be provided two sessions of free health and fitness evaluation with an interval of three months (12 weeks).

Interventions

A 12-week (45 min per day, 5 days per week) instructor-led Tai Chi training program was conducted in the Tai Chi group. Of the 5 days of exercise, 3 days were led by qualified instructors, and 2 other days for self-practice. Each session consisted of a 10-min standard warm-up, 30-min of Tai Chi exercise, and 5-min cool down stretching. The modified 32 Yang-style Tai Chi Chuan was used, because it could be learned within a relatively short time, and has been widely promoted in HK community. An exercise log was used to record the actual implementation of the training (instructor-led \& self-practice).

Tai Chi Group

A 12-week (45 min per day, 5 days per week) instructor-led brisk walking training program was conducted in the walking group. Of the 5 days of exercise, 3 days were led by qualified instructors, and 2 other days for self-practice. Each session consisted of a 10-min standard warm-up, 30-min of walking exercise, and 5-min cool down stretching. An exercise log was used to record the actual implementation of the training (instructor-led \& self-practice).

Walking Group

Eligibility Criteria

Age36 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • residents of large housing estates in the Shatin district
  • physical inactivity
  • no exercise habits

You may not qualify if:

  • cardiovascular diseases
  • pulmonary diseases
  • neurological disorder
  • musculoskeletal disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chinese University of Hong Kong

Hong Kong, Hong Kong

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Stanley Sai-Chuen Hui, EdD

    Chinese University of Hong Kong

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 10, 2014

First Posted

June 16, 2014

Study Start

January 1, 2005

Primary Completion

August 1, 2006

Study Completion

August 1, 2006

Last Updated

August 20, 2014

Record last verified: 2014-08

Locations