Transversus Abdominis Plane Block Versus Caudal Epidural for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Sponsor study identifier
interventional
45
1 country
1
Study Start
January 2011
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2013
Actual (reported)Study Completion
May 2014
Actual (reported)Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia. Complications associated with TAPB are very rare and pose a lower overall risk to the patient receiving a TAPB versus a caudal block, which is considered the gold standard for pediatric lower abdominal regional anesthesia. Our study hypothesis was that TAPB would be equivalent to caudal block initially in providing postoperative pain control but would show improved pain relief beyond the anticipated caudal duration.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2014
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2011
Date type not reportedThis date has not been verified as actual or estimated.
December 2013
Actual (reported)May 2014
Actual (reported)May 29, 2014
Actual (reported)June 11, 2014
Actual (reported)Narcotic requirement
Narcotic requirement was recorded at 24 hours from the time of the block placement.
24 hours post intervention
episodes of nausea/vomiting
24 hours
anti-spasmodic requirement
24 hours post intervention
Pain Scores
24 hours post intervention
Transversus Abdominis Plane Block TAPB Ultrasound guided TAPB
Caudal Epidural Block Caudal Block Neuraxial Block Ultrasound Guided Caudal Block
Ultrasound Guided Caudal Block
Ultrasound Guided Transversus Abdominis Plane Block
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Wolfson Children's Hospital, Baptist Medical Center- Downtown, 800 Prudential Drive
Jacksonville, Florida, 32207, United States
Tripi PA, Palmer JS, Thomas S, Elder JS. Clonidine increases duration of bupivacaine caudal analgesia for ureteroneocystostomy: a double-blind prospective trial. J Urol. 2005 Sep;174(3):1081-3. doi: 10.1097/01.ju.0000169138.90628.b9.
Vetter TR, Carvallo D, Johnson JL, Mazurek MS, Presson RG Jr. A comparison of single-dose caudal clonidine, morphine, or hydromorphone combined with ropivacaine in pediatric patients undergoing ureteral reimplantation. Anesth Analg. 2007 Jun;104(6):1356-63, table of contents. doi: 10.1213/01.ane.0000261521.52562.de.
Robert B Bryskin, MD
Nemours Children's Clinic
45 participants (actual enrollment reported by the registry).
First Submitted
May 29, 2014
First Posted
June 11, 2014
Study Start
January 2011
Date type not reportedThis date has not been verified as actual or estimated.
Postoperative Quality of Recovery After General Anesthesia With Remimazolam
Contact the study team to confirm eligibility.
Bryskin RB, Londergan B, Wheatley R, Heng R, Lewis M, Barraza M, Mercer E, Ye G. Transversus Abdominis Plane Block Versus Caudal Epidural for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial. Anesth Analg. 2015 Aug;121(2):471-8. doi: 10.1213/ANE.0000000000000779.
Primary Completion
December 2013
Actual (reported)Study Completion
May 2014
Actual (reported)Last Updated
June 11, 2014
Record last verified: 2014-06
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Source: ClinicalTrials.gov.
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