Speech Therapy for Aphasia: Comparing Two Treatments
PMvSFA
A Prospective, Controlled Study of Rehabilitation of Anomia in Aphasia
1 other identifier
interventional
58
1 country
1
Brief Summary
This is a behavioral speech therapy trial for individuals who have suffered a stroke on the left side of the brain and have difficulty speaking. The name of this disorder is called "aphasia." Individuals in this study will receive one of two treatments. The first is a phonological (sound level) treatment and the second is a semantic (word level) treatment. Individuals in both groups will receive 60 hours of therapy for free (2 hours/day, 5 days/week, 6 weeks).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable stroke
Started Mar 2014
Longer than P75 for not_applicable stroke
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 11, 2014
CompletedFirst Submitted
Initial submission to the registry
March 20, 2014
CompletedFirst Posted
Study publicly available on registry
June 3, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 21, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
September 29, 2017
CompletedResults Posted
Study results publicly available
September 6, 2019
CompletedSeptember 6, 2019
July 1, 2019
3.4 years
March 20, 2014
June 18, 2018
July 26, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Spoken Word Production (Confrontation Naming)
Reporting a change in percent correct scores pre-treatment versus 3-months post treatment. (0-100% scale)
Pretreatment to 3 months following treatment termination change
Secondary Outcomes (2)
Response Latency
Pretreatment to 3 months following treatment termination change
Verbs Correctly Named
Pretreatment to 3 months following treatment termination change
Study Arms (2)
Phonomotor therapy
EXPERIMENTALExperimental group
Semantic Feature Analysis therapy
ACTIVE COMPARATORCurrent standard of care therapy
Interventions
Control therapy; current standard of care therapy
Eligibility Criteria
You may qualify if:
- Single, left-hemisphere stroke
- English as primary language prior to stroke
You may not qualify if:
- Other neurological disorders
- Untreated depression
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- VA Office of Research and Developmentlead
- Portland State Universitycollaborator
- University of Washingtoncollaborator
Study Sites (1)
VA Puget Sound Health Care System Seattle Division, Seattle, WA
Seattle, Washington, 98108, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Diane Kendall
- Organization
- University of Washington
Study Officials
- PRINCIPAL INVESTIGATOR
Diane L. Kendall, PhD
VA Puget Sound Health Care System Seattle Division, Seattle, WA
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- FED
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 20, 2014
First Posted
June 3, 2014
Study Start
March 11, 2014
Primary Completion
August 21, 2017
Study Completion
September 29, 2017
Last Updated
September 6, 2019
Results First Posted
September 6, 2019
Record last verified: 2019-07
Data Sharing
- IPD Sharing
- Will not share