NCT02150044

Brief Summary

This was a non-significant risk (NSR), prospective, multi-center, single arm clinical trial that aimed to evaluate safety and performance of the Acclarent Tympanostomy Tube Delivery System (TTDS).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
29

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2010

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2010

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2010

Completed
3.6 years until next milestone

First Submitted

Initial submission to the registry

May 27, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 29, 2014

Completed
4 months until next milestone

Results Posted

Study results publicly available

September 25, 2014

Completed
Last Updated

July 12, 2024

Status Verified

July 1, 2024

Enrollment Period

8 months

First QC Date

May 27, 2014

Results QC Date

June 26, 2014

Last Update Submit

July 10, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ear Outcome Success

    Ear Outcome Success is successful delivery of the tympanostomy tube (TT) across the tympanic membrane (TM) per ear. This endpoint was evaluated for the 13 study cohort subjects only (not the 16 lead-in subjects).

    Day 0 (at procedure visit)

Secondary Outcomes (2)

  • Procedure Success

    Day 0 (at procedure visit)

  • Tube Retention

    1 week

Study Arms (1)

Tympanostomy tube

EXPERIMENTAL

Performance and safety of tympanostomy tube delivery system

Device: Acclarent Tympanostomy Tube Delivery System (TTDS).

Interventions

tympanostomy tube delivery system

Tympanostomy tube

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with either chronic otitis media with effusion (OME) or recurrent acute otitis media (AOM) and scheduled to undergo tympanostomy tube insertion

You may not qualify if:

  • History of sensitivity or reaction to anesthesia chosen for the procedure
  • Markedly atrophic, mono- or bimeric, severely retracted, atelectatic or perforated tympanic membrane
  • Otitis externa
  • Active acute otitis media
  • Otitis media pathology requiring T-tubes
  • Stenosed ear canal
  • Anatomy that precludes sufficient visualization of and access to the tympanic membrane
  • Anatomy that necessitates tympanostomy tube placement in the posterior half of the tympanic membrane

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Unknown Facility

Kirkland, Washington, 98034, United States

Location

MeSH Terms

Conditions

Otitis Media

Condition Hierarchy (Ancestors)

OtitisEar DiseasesOtorhinolaryngologic Diseases

Results Point of Contact

Title
Director of Clinical Research
Organization
Acclarent, Inc.

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 27, 2014

First Posted

May 29, 2014

Study Start

February 1, 2010

Primary Completion

October 1, 2010

Study Completion

November 1, 2010

Last Updated

July 12, 2024

Results First Posted

September 25, 2014

Record last verified: 2024-07

Locations