EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).
1 other identifier
interventional
40
1 country
1
Brief Summary
The hypothesis is that Etoricoxib act as an adjuvant to SRP in alleviating periodontal inflammation by:
- 1.improving clinical periodontal parameters and,
- 2.improving the salivary SOD levels.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_4
Started Jan 2013
Shorter than P25 for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2013
CompletedFirst Submitted
Initial submission to the registry
May 26, 2014
CompletedFirst Posted
Study publicly available on registry
May 29, 2014
CompletedMay 29, 2014
May 1, 2014
5 months
May 26, 2014
May 26, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
change from baseline in salivary SOD level
3 months
Study Arms (2)
Etoricoxib
EXPERIMENTALEtoricoxib 60 mg once daily
matching placebo
PLACEBO COMPARATORmatching placebo once daily
Interventions
Eligibility Criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Tatyasaheb kore Dental College And Research Centre
Kolhāpur, Maharashtra, 416137, India
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Dr.Sumit S. Shetgar, BDS
Tatyasaheb Kore Dental College And Research Centre
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- BDS (Post graduate student
Study Record Dates
First Submitted
May 26, 2014
First Posted
May 29, 2014
Study Start
January 1, 2013
Primary Completion
June 1, 2013
Study Completion
June 1, 2013
Last Updated
May 29, 2014
Record last verified: 2014-05