NCT02148172

Brief Summary

While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes. Unusually high risks of early-onset osteoarthritis and re-injury, and low rate of return to sport following ACLR all seem to be related to a chronic tendency to land stiff-legged from a jump or hop, which itself may be due to fear of re-injury. Decreased knee bending for force absorption simultaneously decreases performance level and increases risk for injury and arthritic changes. The purpose of the proposed study is to compare a current best-practice plyometric training program to one utilizing body weight support to increase repetition and improve performance in the initial phases. The investigators hypothesize that we will see larger improvements in absorptive capacity of the knee and better confidence in activity immediately following body weight support training, as well as improved retention of training effects after a two-month period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
47

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 22, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 28, 2014

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

April 25, 2019

Status Verified

April 1, 2019

Enrollment Period

4.9 years

First QC Date

May 22, 2014

Last Update Submit

April 24, 2019

Conditions

Keywords

Kneeplyometricsmotor learningpsychological factors

Outcome Measures

Primary Outcomes (3)

  • Change in sagittal plane knee kinetics and kinematics

    Baseline and after 8 weeks of training

  • Change in psychological readiness for sports activities via survey scores

    baseline and after 8 weeks of training

  • Change in motor patterning via electromyography of quadriceps and hamstring muscles

    Baseline and after 8 weeks of training

Secondary Outcomes (3)

  • Retention of Biomechanical Adaptions in Knee kinetics and kinematics

    Change from end of 8 weeks of training to 2 month follow-up

  • Retention of adaptations in Psychological Readiness for Sport via survey

    Change from end of 8 weeks of training to 2 month follow-up

  • Retention of adaptations in motor patterning via electromyography

    Change from end of 8 weeks of training to 2 month follow-up

Study Arms (2)

Standard Plyometric Training

ACTIVE COMPARATOR

Participants will undergo treatment 2 times a week for 8 weeks with plyometric exercises deemed to be consistent with best practice delivered at a standard dosage of sets and repetitions.

Procedure: Standard Plyometric Training

Plyometric Training with BWS

EXPERIMENTAL

Participants will undergo treatment 2 times a week for 8 weeks with plyometric exercises deemed to be consistent with best practice with a treatment volume of sets and repetitions that exceeds standard practice. Higher number of practice trials will be completed with body weight support (BWS) to reduce load. Participants will start at 30 percent of body weight and will be slowly weaned away over time.

Procedure: Plyometric Training with BWS

Interventions

Participants will undergo individualized practice exercises of jumping, hopping, and cutting tasks consistent with standard published exercises.

Standard Plyometric Training

Participants will undergo individualized practice exercises of jumping, hopping, and cutting tasks consistent with standard published exercises while their body weight is supported via adjustable harness.

Plyometric Training with BWS

Eligibility Criteria

Age12 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • speak and understand English
  • age between 12-35 years
  • unilateral anterior cruciate ligament reconstruction between 6-48 months prior
  • activity level greater than or equal to level 5 on the Tegner Activity Scale

You may not qualify if:

  • Weight in excess of 300 pounds (136 kg)
  • contralateral/bilateral ACL reconstruction or an unreconstructed ACL injury
  • history of a posterior cruciate ligament injury
  • lower extremity of back injury or other condition (e.g. cerebral palsy) that has limited their normal activities of daily living within the last 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Montana, Movement Science Laboratory

Missoula, Montana, 59812, United States

Location

Related Publications (1)

  • Elias ARC, Harris KJ, LaStayo PC, Mizner RL. Clinical Efficacy of Jump Training Augmented With Body Weight Support After ACL Reconstruction: A Randomized Controlled Trial. Am J Sports Med. 2018 Jun;46(7):1650-1660. doi: 10.1177/0363546518759052. Epub 2018 Mar 20.

MeSH Terms

Conditions

Anterior Cruciate Ligament InjuriesKnee Injuries

Interventions

Plyometric Exercise

Condition Hierarchy (Ancestors)

Leg InjuriesWounds and Injuries

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ryan L Mizner, PT, PhD

    University of Montana

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

May 22, 2014

First Posted

May 28, 2014

Study Start

January 1, 2014

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

April 25, 2019

Record last verified: 2019-04

Locations