Longitudinal Study of Primary Osteoporosis in Shanghai Postmenopausal Women
1 other identifier
observational
3,000
1 country
1
Brief Summary
To popularize knowledge of prevention and health care of osteoporosis.To investigate the prevalence of primary osteoporosis in community residents.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2014
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 14, 2014
CompletedFirst Posted
Study publicly available on registry
May 20, 2014
CompletedStudy Start
First participant enrolled
June 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2018
CompletedMay 20, 2014
May 1, 2014
3.5 years
May 14, 2014
May 15, 2014
Conditions
Outcome Measures
Primary Outcomes (1)
Bone Mineral Density
baseline
Secondary Outcomes (6)
SF-36
baseline
international osteoporosis foundation ONE-MINUTE OSTEOPOROSIS RISK TEST
baseline
Markers of bone metabolism test
baseline
EQ-5D
baseline
Hepatic-renal function test
baseline
- +1 more secondary outcomes
Study Arms (1)
osteoprosis research
Eligibility Criteria
Randomly selected two communities in Xuhui District to investigate.
You may qualify if:
- Had clinical diagnosis of osteoporosis.
- With Bone Mineral Density by dual energy X-ray examination, T value \<-2.5 or less.
- Be willing to and be able to join in the study and signed Informed consent.
You may not qualify if:
- Excluding the impact of endocrine diseases of bone metabolism (gonadal, adrenal, parathyroid and thyroid disease), rheumatoid arthritis and other autoimmune diseases that affect the absorption of calcium and vitamin D and regulation of the digestive tract and kidney disease, multiple myeloma and other malignant diseases, long-term use of corticosteroids or other drugs affecting bone metabolism, and a variety of congenital and acquired diseases of bone metabolism.
- if they were unable to complete the study survey.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Longhua Hospital
Shanghai, Shanghai Municipality, 200032, China
Related Publications (1)
Xu H, Zhang H, Aimaiti R, Yuan C, Cai F, Wang H, Ji J, Liang J, Cui J, Wang J, Shu B, Xu H, Liang Q, Shi Q, Sun Q, Fang R, Tang D, Wang Y; China Community-based Cohort of Osteoporosis (CCCO) collaborative group. Early-life malnutrition exposure associated with higher osteoporosis risk in adulthood: a large-scale cross-sectional study. Int J Surg. 2025 Jan 1;111(1):190-199. doi: 10.1097/JS9.0000000000002057.
PMID: 39196877DERIVED
Biospecimen
Basal whole blood is collected for serum and DNA extraction.
Study Officials
- PRINCIPAL INVESTIGATOR
Yongjun Wang, Dr
Study Principal Investigator Longhua Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Vice director
Study Record Dates
First Submitted
May 14, 2014
First Posted
May 20, 2014
Study Start
June 1, 2014
Primary Completion
December 1, 2017
Study Completion
December 1, 2018
Last Updated
May 20, 2014
Record last verified: 2014-05