NCT02138968

Brief Summary

The study intervention improves functional capacity and delays frailty status in pre-frail elderly subjects.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
170

participants targeted

Target at P75+ for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

May 12, 2014

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 15, 2014

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
Last Updated

September 1, 2015

Status Verified

August 1, 2015

Enrollment Period

1.9 years

First QC Date

May 12, 2014

Last Update Submit

August 31, 2015

Conditions

Keywords

Pre-frailtyFrailExerciseNutritional assessmentFunctional capacity

Outcome Measures

Primary Outcomes (2)

  • Frailty according to L.Fried criteria (questionnaire).

    L.Fried frailty criteria: (Robust: 0 criteria; Pre-frail: 1-2 criteria; Frail: \>=3 criteria) 1. Weight loss 2. Fatigue 3. Poor physical activity 4. Low walking speed 5. Low muscle strength Reference of L.Fried: J Gerontol A Biol Sci Med Sci. 2001 Mar; 56(3):M146-56. PMID: 11253156.

    One year

  • Functional capacity according to Barthel score and Timed up and go test.

    Barthel score and Timed up and go test.

    One year

Secondary Outcomes (4)

  • Nutritional status according to MNA-sf.

    One year

  • Quality of live according to EuroQoL.

    One year

  • Mortality

    One year

  • Health resource consumption (composite measure)

    One year

Other Outcomes (1)

  • Pain according Visual Analog Scale.

    One year

Study Arms (2)

Multidimensional intervention

EXPERIMENTAL

Multidimensional intervention based on: good control of baseline diseases, review of medication adequacy, exercise program, nutritional assessment and control, social assessment and control.

Other: Multidisciplinary intervention

Usual care

NO INTERVENTION

Usual care

Interventions

Multidimensional intervention based on: good control of baseline diseases, review of medication adequacy, exercise program, nutritional assessment and control, social assessment and control.

Multidimensional intervention

Eligibility Criteria

Age70 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • More than 70 years consulting in primary care
  • Non institutionalized
  • Pre-frailty according to L.Fried criteria (1 or 2 criteria)
  • Signed informed consent

You may not qualify if:

  • Patient not able to stand by himself/herself
  • Dementia
  • Palliative care or life expectancy less than 6 months
  • Blind patient
  • unstable clinical situation
  • Participation in other programs, studies or trials for elderly people

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Consorci Sanitari del Maresme

Mataró, Barcelona, 08304, Spain

Location

Related Publications (1)

  • Serra-Prat M, Sist X, Domenich R, Jurado L, Saiz A, Roces A, Palomera E, Tarradelles M, Papiol M. Effectiveness of an intervention to prevent frailty in pre-frail community-dwelling older people consulting in primary care: a randomised controlled trial. Age Ageing. 2017 May 1;46(3):401-407. doi: 10.1093/ageing/afw242.

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Mateu Serra-Prat, PhD

    Fundació Salut del Consorci Sanitari del Maresme

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2014

First Posted

May 15, 2014

Study Start

September 1, 2013

Primary Completion

August 1, 2015

Last Updated

September 1, 2015

Record last verified: 2015-08

Locations