NCT02133235

Brief Summary

The need of fiberoptic bronchoscopy for placing an endobronchial blocker. Endobronchial blockers (EBB) have been presented effective and safe alternative for lung separation in vedio-assisted thoracoscopic (VATS) operations. In this study, the investigators will randomize the patients receiving VATS operation with EBB into two groups: one group will receive the conventional bronchoscopic guided EBBs placement, the other group receive two step procedure without confirmation by fiberoptic bronchoscopy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
112

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2014

Completed
3 days until next milestone

Study Start

First participant enrolled

May 1, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 7, 2014

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
6 months until next milestone

Results Posted

Study results publicly available

November 23, 2015

Completed
Last Updated

November 23, 2015

Status Verified

October 1, 2015

Enrollment Period

1.1 years

First QC Date

April 28, 2014

Results QC Date

June 30, 2015

Last Update Submit

October 20, 2015

Conditions

Keywords

endobronchial blockerlung separationvedio-assisted thoracic operation

Outcome Measures

Primary Outcomes (2)

  • Surgical Grading for Lung Isolation

    A: Optimal; B: Lung distension; C: Poor endobronchial blocker placement

    10-15 minutes

  • Time Required for Proper Placement of the Endobronchial Blocker

    10-15 minutes

Study Arms (2)

conventional

ACTIVE COMPARATOR

insertion of endobronchial blocker and auscultation, fiberoptic confirmation and reposition

Procedure: conventional

auscultation

EXPERIMENTAL

insertion endobronchial blocker by auscultation without conventional bronchoscopic reposition

Procedure: auscultation

Interventions

conventionalPROCEDURE

insertion endobronchial blocker with the guidance of fiberoptic bronchoscopy

conventional
auscultationPROCEDURE

insertion endobronchial blocker by auscultation, without the guidance of fiberoptic bronchoscopy

auscultation

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Lung separation by endobronchial blockers

You may not qualify if:

  • Lung separation by conventional double lumen tube Lung separation with endobronchial blockers through

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan, 100, Taiwan

Location

Related Publications (1)

  • Wang ML, Wang YP, Hung MH, Hsu HH, Chen JS, Yang FS, Cheng YJ. Is fibre-optic bronchoscopy necessary to confirm the position of rigid-angled endobronchial blockers before thoracic surgery? A randomized controlled trial. Eur J Cardiothorac Surg. 2018 Jan 1;53(1):241-246. doi: 10.1093/ejcts/ezx260.

MeSH Terms

Conditions

Lung NeoplasmsThoracic Diseases

Interventions

Congresses as TopicAuditory Perception

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

OrganizationsHealth Care Economics and OrganizationsVestibulocochlear Physiological PhenomenaPhysiological Phenomena

Results Point of Contact

Title
YJ Cheng
Organization
NTUH

Study Officials

  • Ya-Jung Cheng

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2014

First Posted

May 7, 2014

Study Start

May 1, 2014

Primary Completion

June 1, 2015

Study Completion

June 1, 2015

Last Updated

November 23, 2015

Results First Posted

November 23, 2015

Record last verified: 2015-10

Locations