Eye Rubbing and Transient Change in Corneal Parameters
Relationship Between Eye Rubbing and Transient Changes in Corneal Parameters in Healthy Volunteers: A Randomised-Controlled Trial
1 other identifier
interventional
52
1 country
1
Brief Summary
This study addresses the research question: How does eye rubbing affect corneal (clear part of eye) parameters in healthy volunteers The study objectives are:
- 1.To determine the corneal changes following eye rubbing
- 2.To assess tear film changes following eye rubbing
- 3.To investigate if there is an association between eye rubbing and axial length of the eye.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2014
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2014
CompletedFirst Submitted
Initial submission to the registry
April 30, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2014
CompletedFirst Posted
Study publicly available on registry
May 6, 2014
CompletedDecember 2, 2014
November 1, 2014
2 months
April 30, 2014
November 28, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
changes in corneal parameters following eye rubbing
To study the change in anterior and posterior corneal parameters
pre and post eye rubbing for 2 minutes
Secondary Outcomes (1)
Relationship between eyeball dimensions following eye rubbing
pre and post eye rubbing for 2 minutes
Study Arms (2)
Eye rubbing intervention
EXPERIMENTALeye rubbing performed for 1 minute in horizontal direction, clockwise rest for 5 seconds eye rubbing for a further 1 minute
No eye rubbing
ACTIVE COMPARATORno eye rubbing - comparator
Interventions
eye rubbing for 1 minute in horizontal direction clockwise, 5 second rest \& eye rubbing for a further 1 minute.
Eligibility Criteria
You may qualify if:
- aged 18 years or above healthy
You may not qualify if:
- aged less than 18 years
- subjects with: terminal illness, poor English language skills or a confused state history of previous ocular problems or surgeries history of contact lens wear not will to undergo simple \& quick scans and eye examinations
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Sussex Eye Hospital
Brighton, East Sussex, BN2 5BF, United Kingdom
Related Publications (1)
Chervenkoff JV, Hawkes E, Ortiz G, Horney D, Nanavaty MA. A randomized, fellow eye, comparison of keratometry, aberrometry, tear film, axial length and the anterior chamber depth after eye rubbing in non-keratoconic eyes. Eye Vis (Lond). 2017 Aug 14;4:19. doi: 10.1186/s40662-017-0084-8. eCollection 2017.
PMID: 28815191DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mayank Nanavaty, Consultant
Sussex Eye Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Consultant Ophthalmic Surgeon
Study Record Dates
First Submitted
April 30, 2014
First Posted
May 6, 2014
Study Start
March 1, 2014
Primary Completion
May 1, 2014
Study Completion
May 1, 2014
Last Updated
December 2, 2014
Record last verified: 2014-11