The Effect of Walking Meditation Training on Glycemic Control and Vascular Function in Patients With Type 2 Diabetes

NCT02123901 | Completed

• 1 other identifier: SPSC-1
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Walking Meditation training would yield more favorable adaptations than walking alone in improving glycemic control and vascular function in patients with type 2 diabetes.

Conditions

Type 2 Diabetes

Keywords

Mind and body Exercise; Flow mediated dilation; Diabetes

Outcome Measures

Primary Outcomes (2)

• Change from baseline in glycemic control

  The glycemic control will be quantified using blood samples. Fasting blood glucose, HbA1c, and insulin will be measured with standard procedures at the clinical laboratory (Bria Lab, Bangkok, Thailand).Homeostasis model assessment (HOMA), the parameter for insulin resistance, will be calculated by using equation of \[Fasting glucose (mg/dL) × Insulin level (uU/mL) / 405\].

  Baseline, Week 12

• Change from baseline in vascular reactivity

  Vascular reactivity or brachial artery flow-mediated dilatation (FMD) will be assessed with the ultrasound equipment (CX50, Philips, USA), using the blood occlusion technique on the right forearm. The brachial artery will be imaged above the antecubital fossa in the longitudinal plane. Baseline data will be monitored and the cuff placed around the right forearm will be inflated to 50 mmHg above systolic blood pressure for 5 minutes and then deflated for 5 minutes of recovery. FMD will be calculated from the formula FMD=(D2-D1)x100/D1 when D1 is the brachial artery diameter at baseline, D2 is the maximal post-occlusion brachial artery diameter

  baseline, week 12

Secondary Outcomes (5)

• Change from baseline in stress indicators

  Baseline, Week 12

• Change from baseline in physical fitness

  Baseline, Week 12

• Change from baseline in Peripheral arterial stiffness

  Baseline, Week 12

• Change from baseline in ankle-brachial index.

  Baseline, Week 12

• Change from baseline in blood chemistry

  Baseline, Week 12

Study Arms (2)

Walking meditation & Walking

EXPERIMENTAL

Other: Walking Meditation; Other: Walking

Walking meditation & No exercise

ACTIVE COMPARATOR

Other: Walking Meditation; Other: No exercise

Interventions

Walking Meditation OTHER

Walking Meditation training program will be based on aerobic walking exercise combined with Buddhist meditation. The subjects will perform walking on the treadmill while concentrated on foot stepping by voiced "Budd" and "Dha" with each foot step that contacted the floor to practice mindfulness while walking. Walking Meditation will be conducted at mild to moderate intensity (50-60% maximum heart rate) and in phase 2 (week 7-12), the training intensity will be increased to moderate intensity (60-70% maximum heart rate). In both phases the training will be performed for 30 minutes, 3 times per week.

Also known as: Buddhist Walking Meditation

Walking meditation & No exercise; Walking meditation & Walking

Walking OTHER

Walking training program will be based on aerobic walking exercise. The subjects will perform walking on the treadmill and conducted at mild to moderate intensity (50-60% maximum heart rate) and in phase 2 (week 7-12), the training intensity will be increased to moderate intensity (60-70% maximum heart rate). In both phases the training will be performed for 30 minutes, 3 times per week.

Walking meditation & Walking

No exercise OTHER

Sedentary life style.

Walking meditation & No exercise

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may not qualify if:

• Participants were excluded if they dropped out or completed less than 80% of the training schedule.

Sponsors & Collaborators

• Chulalongkorn University: lead

Study Sites (1)

The Primary Health Promoting Hospital

Prapadang, Changwat Samut Prakan, 10130, Thailand

Location

Related Publications (1)

• Mitranun W, Deerochanawong C, Tanaka H, Suksom D. Continuous vs interval training on glycemic control and macro- and microvascular reactivity in type 2 diabetic patients. Scand J Med Sci Sports. 2014 Apr;24(2):e69-76. doi: 10.1111/sms.12112. Epub 2013 Sep 17.

  PMID: 24102912 BACKGROUND

Related Links

• Related Info

MeSH Terms

Conditions

Diabetes Mellitus, Type 2; Diabetes Mellitus

Interventions

Walking

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Locomotion; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise; Motor Activity

Study Officials

• Daroonwan Suksom, Ph.D.

  Faculty of Sports Science, Chulalongkorn University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Faculty of Sports Science

Study Record Dates

• First Submitted: April 18, 2014
• First Posted: April 28, 2014
• Study Start: December 1, 2013
• Primary Completion: October 1, 2014
• Study Completion: February 1, 2015
• Last Updated: September 16, 2015

Record last verified: 2013-08

Locations

TH (1)