NCT02123238

Brief Summary

The study aims to evaluate the effect of non-supine positioning in the treatment of surgical patients with obstructive sleep apnea. The hypothesis is that non-supine positioning will result in a decrease in acute hypoxic events, defined as the number of apneas/hypopneas per hour of sleep.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2014

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2014

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

April 23, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 25, 2014

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

September 15, 2015

Status Verified

September 1, 2015

Enrollment Period

1.2 years

First QC Date

April 23, 2014

Last Update Submit

September 14, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Acute Hypoxic Index (AHI)

    study will look at the effect of bed positioning on Acute Hypoxic Index (AHI), which is defined as the number of apneas/hypopneas per hour of sleep

    3 days

Study Arms (3)

Control

OTHER

standard of care positioning (0 degree)

Other: bed positioning

30 degree

OTHER

30 degree bed positioning

Other: bed positioning

60 degree

OTHER

60 degree bed positioning

Other: bed positioning

Interventions

30 degree60 degreeControl

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Minimum 1 night postoperative hospital stay
  • More than 18 and less than 80 years old
  • Identified as high risk of OSA (SACS \> 15) or a history of OSA without CPAP treatment

You may not qualify if:

  • Unwilling or unable to give informed consent
  • Undergoing nasal, eye, head/neck surgery, intracranial or cardiac/thoracic surgery
  • Currently undergoing treatment for sleep apnea including CPAP
  • Requiring prolonged postoperative ventilation
  • NYHA functional class III and IV
  • Valvular heart disease, dilated cardiomyopathy, implanted cardiac pacemaker, or unstable angina
  • Myocardial infarction or cardiac surgery within 3 months
  • Chronic obstructive pulmonary disease, or asthma
  • Presence of tracheostomy, facial, neck, or chest wall abnormalities
  • Abdominal aortic aneurysm surgery, chemotherapy, or immunosuppressive therapy within 3 months
  • Visiting preoperative clinic less than 3 days before surgery
  • Requiring postoperative nasogastric tube

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Englewood Hospital and Medical Center

Englewood, New Jersey, 07631, United States

Location

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Aryeh Shander, MD

    Englewood Hospital and Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 23, 2014

First Posted

April 25, 2014

Study Start

April 1, 2014

Primary Completion

July 1, 2015

Study Completion

December 1, 2015

Last Updated

September 15, 2015

Record last verified: 2015-09

Locations