Trials Sponsors Conditions Drugs Pricing

Conditions

Twin Twin Transfusion Syndrome

Keywords

Twin twin transfusion syndromeSequential laser photocoagulation of communicating vessels

Outcome Measures

Primary Outcomes (1)

To compare donor intrauterine survival (alive at birth) for those undergoing SQLPCV vs. SLPCV.
A comparison of donor survival at birth will be made between subjects assigned to the sequential (SQLPCV) procedure versus those assigned to the selective (SLPCV) procedure.
Birth

Secondary Outcomes (1)

Surgical complications
21 post-operative days

Other Outcomes (1)

Fetal/neonatal/infant outcomes
Birth to 6 months of life

Study Arms (2)

Selective procedure

ACTIVE COMPARATOR

Selective laser photocoagulation of communicating vessels.

Procedure: Selective laser photocoagulation of communicating vessels

Sequential procedure

EXPERIMENTAL

Sequential laser photocoagulation of communicating vessels

Procedure: Sequential laser photocoagulation of communicating vessels.

Interventions

Sequential laser photocoagulation of communicating vessels.Procedure

Sequential procedure

Selective laser photocoagulation of communicating vesselsProcedure

Selective procedure

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age16 Years - 55 Years

Sexfemale

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

Gestational age: 16 weeks, 0 days to 26 weeks, 0 days.
Confirmed TTTS patients, who by definition meet the following sonographic criteria:

Sponsors & Collaborators

University of Southern California
Otherlead

Study Sites (1)

Hollywood Presbyterian Medical Center

Los Angeles, California, 90027, United States

MeSH Terms

Conditions

Fetofetal Transfusion

Condition Hierarchy (Ancestors)

Anemia, NeonatalAnemiaHematologic DiseasesHemic and Lymphatic DiseasesInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

Ramen Chmait, MD
University of Southern California
PRINCIPAL INVESTIGATOR

Enrollment

642 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Associate Professor, Clinical Obstetrics & Gynecology, Pediatrics, and Surgery

Study Record Dates

First Submitted

April 16, 2014

First Posted

April 24, 2014

Study Start

June 9, 2010

Actual (reported)

Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Selective procedure

Sequential procedure

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Selective procedure

Sequential procedure

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations