Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty

NCT02102581 | Completed DMC

• 1 other identifier: Orthopedic deparment
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation. Operation time, total measured blood loss, intraoperative transfusion volume, and complication were recorded. Hemoglobin level was recorded preoperatively and in postoperative 1, 3, 7 and 14 days, and the limb circumference, pain score, and knee joint range of motion were also recorded preoperatively and in postoperative 3,7 and 14 days.Investigators want to observe the difference between the two groups. Hypothesis was made that patients in group B may feel better after operation for short time use of tourniquet.

Conditions

Osteoarthritis

Keywords

Tourniquet; Total knee arthroplasty; Blood loss; Limb swelling; Limb circumference

Outcome Measures

Primary Outcomes (1)

• the limb circumference at 10 cm above the knee at postoperative day 1,3,7 and 14

  14 days after the surgery

Study Arms (1)

short time tourniquet

60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation(short time).

Procedure: short time tourniquet

Interventions

short time tourniquet PROCEDURE

short time tourniquet: the tourniquet starting from the implantation of prosthesis to the completion of the operation.

short time tourniquet

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

60 consecutive patients who underwent routine TKA were included in this prospective randomized study.

You may qualify if:

• Patients eligible for the study included those who underwent initial unilateral TKA for osteoarthritis or rheumatoid arthritis.

You may not qualify if:

• Patients with diabetes, hemorrhagic disease, Hb \< 100 g/L, peripheral neurovascular disease, malignant tumors, history of vascular thrombosis, or history of infection in the lower limb were excluded

Sponsors & Collaborators

• Peking Union Medical College Hospital: lead

Study Sites (1)

orthopedic department, Peking Union Medical College Hospital

Beijing, 100730, China

Location

Related Publications (1)

• Fan Y, Jin J, Sun Z, Li W, Lin J, Weng X, Qiu G. The limited use of a tourniquet during total knee arthroplasty: a randomized controlled trial. Knee. 2014 Dec;21(6):1263-8. doi: 10.1016/j.knee.2014.08.002. Epub 2014 Sep 9.

  PMID: 25212990 DERIVED

MeSH Terms

Conditions

Osteoarthritis; Hemorrhage

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Yu Fan, MD

  an orthopaedist of Peing Union Medical College Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 14 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 24, 2014
• First Posted: April 3, 2014
• Study Start: February 1, 2011
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2011
• Last Updated: April 3, 2014

Record last verified: 2014-03

Locations

CN (1)