NCT02098369

Brief Summary

About 1 million individuals in the US have a prescription for supplemental oxygen (O2). Using O2 can prolong life and increase quality of life. Patients often do not use their oxygen as prescribed, which means that they are not benefiting as much as they could be from this therapy. The purpose of this study is to evaluate whether a PEer-Led O2 Infoline for patients and CAregivers (PELICAN) will increase adherence to supplemental oxygen prescription and improve health in patients with chronic obstructive pulmonary disease (COPD).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
444

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Apr 2015

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 14, 2014

Completed
14 days until next milestone

First Posted

Study publicly available on registry

March 28, 2014

Completed
1 year until next milestone

Study Start

First participant enrolled

April 1, 2015

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

August 6, 2018

Completed
Last Updated

August 6, 2018

Status Verified

November 1, 2017

Enrollment Period

1.4 years

First QC Date

March 14, 2014

Results QC Date

December 30, 2016

Last Update Submit

November 6, 2017

Conditions

Keywords

Chronic obstructive pulmonary disease (COPD)Supplemental oxygenAdherenceTelephonic educationPeer coaching

Outcome Measures

Primary Outcomes (1)

  • Adherence to Supplemental O2 Prescription

    Number of individuals who used the stationary concentrator for a mean of at least 17.7 hours per day

    60 days

Secondary Outcomes (7)

  • PROMIS - Physical Function

    60 days

  • PROMIS - Fatigue

    60 days

  • PROMIS - Emotional Distress - Anxiety

    60 days

  • PROMIS - Sleep Disturbance

    60 days

  • PROMIS - Emotional Distress - Depression

    60 days

  • +2 more secondary outcomes

Study Arms (3)

Usual care

OTHER

Written education material (basic)

Behavioral: Written education material (basic)

Proactive

EXPERIMENTAL

Written education material (basic) Additional education material PELICAN-Proactive \[In addition to the usual care, participants will receive educational material and a proactive telephone peer coaching program (coaches call participants)\]

Behavioral: Written education material (basic)Behavioral: Additional education materialBehavioral: PELICAN-Proactive

Reactive

EXPERIMENTAL

Written education material (basic) Additional education material PELICAN-Reactive \[In addition to the usual care, participants will receive educational material and a reactive telephone peer coaching program (participants call coaches)\]

Behavioral: Written education material (basic)Behavioral: Additional education materialBehavioral: PELICAN-Reactive

Interventions

Education material on COPD distributed to all participants.

ProactiveReactiveUsual care

Additional education material sent to participants in the proactive and reactive arms.

ProactiveReactive

In the proactive arm, calls will be initiated by the coach. The phone calls will involve educational and social support components. PELICAN is grounded on the social cognitive theory of behavior change and seeks to improve patient adherence by addressing patient self-efficacy and outcome expectancy.

Proactive

Participants allocated to the reactive PELICAN group will be offered the opportunity to access the COPD Foundation Infoline toll-free.

Reactive

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older.
  • Physician diagnosis of COPD
  • Physician prescription for home O2 for 24hrs/day, 7 days/week
  • Willing to use home O2.
  • Working telephone number.

You may not qualify if:

  • Unable to read and speak English.
  • Discharge to home hospice or expected survival less than 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Apria Healthcare

Lake Forest, California, 92630, United States

Location

Los Angeles Biomedical Research Institute

Torrance, California, 90502, United States

Location

National Jewish Health

Denver, Colorado, 80206, United States

Location

AlphaNet

Miami, Florida, 33134, United States

Location

COPD Foundation

Miami, Florida, 33134, United States

Location

University of Illinois Hospital

Chicago, Illinois, 60612, United States

Location

Related Publications (1)

  • Prieto-Centurion V, Holm KE, Casaburi R, Porszasz J, Basu S, Bracken NE, Gallardo R 3rd, Gonzalez V, Illendula SD, Sandhaus RA, Sullivan JL, Walsh LJ, Gerald LB, Krishnan JA. A Hybrid Effectiveness/Implementation Clinical Trial of Adherence to Long-Term Oxygen Therapy for Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2023 Nov;20(11):1561-1570. doi: 10.1513/AnnalsATS.202302-104OC.

Related Links

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Alkalies

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Inorganic Chemicals

Results Point of Contact

Title
Jerry A. Krishnan, MD, PhD
Organization
University of Illinois at Chicago

Study Officials

  • Jerry A Krishnan, MD, PhD

    University of Illinois at Chicago

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine and Public Health; Associate Vice Chancellor for Population Health Sciences

Study Record Dates

First Submitted

March 14, 2014

First Posted

March 28, 2014

Study Start

April 1, 2015

Primary Completion

September 1, 2016

Study Completion

October 1, 2016

Last Updated

August 6, 2018

Results First Posted

August 6, 2018

Record last verified: 2017-11

Locations