NCT02097758

Brief Summary

Background: Three-dimensional echocardiographic image for atrial septal defect (ASD) is useful for evaluation of defect size and shape. The investigators suggested optimal device size using three-dimensional transesophageal echocardiographic image and our formula in previous study. Purpose: In this study, the investigators seek to predict the correct device size and confirm the accuracy of the formula that we made before device closure in ASD patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
7mo left

Started Mar 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress96%
Mar 2014Dec 2026

Study Start

First participant enrolled

March 1, 2014

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

March 25, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 27, 2014

Completed
12.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

February 7, 2025

Status Verified

January 1, 2023

Enrollment Period

12.8 years

First QC Date

March 25, 2014

Last Update Submit

February 5, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Successful device implantation

    1 day

Secondary Outcomes (1)

  • Procedure time

    during procedure

Other Outcomes (1)

  • Complications from device

    1 year

Study Arms (1)

transcatheter device closure

EXPERIMENTAL

Choosing device size using three dimensional image and the formula without sizing balloon

Device: Transcatheter device closure

Interventions

Closure of atrial septal defect with device * choosing device size with 3D image and the formula * we do not use sizing balloon for choosing of the device size

transcatheter device closure

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥18 year-old
  • Susceptible indication for atrial septal defect closure
  • Potential candidate for device closure

You may not qualify if:

  • Poor candidate for device closure: multiple ASDs, ect
  • Other heart disease requiring open heart surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Asan Medical Center

Seoul, 138-736, South Korea

RECRUITING

Related Publications (2)

  • Lee PH, Kim GY, Yu JS, Earm I, Kwon KB, Koo HI, Kim TO, Lee S, Sun BJ, Kim DH, Kang DH, Song JK, Song JM. Routine Application of Three-Dimensional Transesophageal Echocardiography-based Device Selection for Transcatheter Closure of Atrial Septal Defect without Balloon Sizing. Eur Heart J Cardiovasc Imaging. 2026 Jan 13:jeag007. doi: 10.1093/ehjci/jeag007. Online ahead of print.

  • Jang JY, Heo R, Cho MS, Bae J, Hong JA, Lee S, Ahn JM, Park DW, Kim DH, Kang DH, Song JK, Song JM. Efficacy of 3D transoesophageal echocardiography for transcatheter device closure of atrial septal defect without balloon sizing. Eur Heart J Cardiovasc Imaging. 2018 Jun 1;19(6):684-689. doi: 10.1093/ehjci/jex153.

MeSH Terms

Conditions

Heart Septal Defects, Atrial

Condition Hierarchy (Ancestors)

Heart Septal DefectsHeart Defects, CongenitalCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Jong-Min Song, MD PhD

    Asan Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jong-Min Song, MD,PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 25, 2014

First Posted

March 27, 2014

Study Start

March 1, 2014

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

February 7, 2025

Record last verified: 2023-01

Locations