NCT02091778

Brief Summary

The primary objective of this post market clinical follow-up (PMCF) investigation is to evaluate performance and safety of fast gelling dressing when used as intended in Diabetic Foot Ulcer (DFU). The primary endpoint will be Changes from baseline in the condition of the peri-wound skin measured by the following variables; maceration, redness/irritation, rash/eczema, blistering, dermatitis, skin stripping, trauma to wound edges and product degradation on the skin

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 18, 2014

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 19, 2014

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2014

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
12 months until next milestone

Results Posted

Study results publicly available

February 23, 2016

Completed
Last Updated

February 23, 2016

Status Verified

March 1, 2014

Enrollment Period

7 months

First QC Date

March 18, 2014

Results QC Date

January 26, 2016

Last Update Submit

January 26, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Peri-wound Skin

    Measured by the following variables; maceration, redness/irritation, rash/eczema, blistering, dermatitis, skin stripping, trauma to wound edges and product degradation on the skin

    12 weeks

Study Arms (1)

Fast Gelling Dressing

EXPERIMENTAL
Device: Fast gelling dressing

Interventions

Fast Gelling Dressing

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Both gender ≥18 years old.
  • Subjects with type 1 or 2 diabetes mellitus.
  • Texas Grade A1 or 2, C1 or 2
  • Exuding diabetic foot ulcer
  • Ulcer localisation; below the ankle
  • Signed Informed Consent.

You may not qualify if:

  • Known allergy/hypersensitivity to the dressing.
  • HbA1c ≥ 10% (86 mmol/mol) (most recent value within 3 months)
  • Wound infection requiring systemic treatment
  • Subjects who will have problems following the protocol.
  • Subjects included in other ongoing clinical investigation at present or during the past 30 days.
  • Toe pressure less than 70 mmHg
  • Clinical suspicion of osteomyelitis (based on probe to bone/radiological changes)
  • Dry wounds

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Royal Infirmary of Edinburgh

Edinburgh, EH16 4SA, United Kingdom

Location

Salford Royal Hospital (NHS) Foundation Trust

Salford, M68hd, United Kingdom

Location

MeSH Terms

Conditions

Diabetic Foot

Condition Hierarchy (Ancestors)

Diabetic AngiopathiesVascular DiseasesCardiovascular DiseasesFoot UlcerLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesDiabetic Neuropathies

Results Point of Contact

Title
Paul Chadwick
Organization
Podiatry and Foot health, Stott Lane Salford ,UK

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 18, 2014

First Posted

March 19, 2014

Study Start

August 1, 2014

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

February 23, 2016

Results First Posted

February 23, 2016

Record last verified: 2014-03

Locations