NCT02091544

Brief Summary

Children and adolescents with overweight and obesity are predisposed to significant health problems. It is known that childhood obesity can adversely affect almost every organ system, and if left untreated, the major impact of childhood overweight is likely to be felt in the next generation of adults. The aim of " Kijk op overgewicht bij kinderen" is to collect and follow-up longitudinal data from a population of different degrees of children with overweight regarding etiological factors, risk factors and early stages of chronic disease in different degrees of childhood overweight.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2013

Completed
6 months until next milestone

First Posted

Study publicly available on registry

March 19, 2014

Completed
13 days until next milestone

Study Start

First participant enrolled

April 1, 2014

Completed
9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2023

Completed
Last Updated

April 30, 2020

Status Verified

April 1, 2020

Enrollment Period

9 years

First QC Date

September 17, 2013

Last Update Submit

April 28, 2020

Conditions

Childhood Obesity

Keywords

overweightobesitychildrenlifestyle intervention

Outcome Measures

Primary Outcomes (1)

  • The number of overweight or obese children

    approximately 10 years

Study Arms (1)

Lifestyle intervention

lifestyle intervention

Other: Lifestyle intervention

Interventions

Lifestyle interventionOTHER
Lifestyle intervention

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

overweight or obese children according to the International Obesity Task Force (IOTF) criteria \< 18 years old.

You may qualify if:

  • Participation in the COACH program
  • Overweight or obesity according to International Obesity Task Force (IOTF) criteria

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maastricht University Medical Center

Maastricht, Limburg, 6202AZ, Netherlands

RECRUITING

Related Publications (7)

  • van Dam MJCM, Pottel H, Delanaye P, Vreugdenhil ACE. The evaluation of kidney function estimation during lifestyle intervention in children with overweight and obesity. Pediatr Nephrol. 2024 Nov;39(11):3271-3278. doi: 10.1007/s00467-024-06435-0. Epub 2024 Jul 4.

    PMID: 38963556DERIVED

  • Lubrecht J, Arayess L, Reijnders D, Hesselink ML, Velde GT, Janse A, von Rosenstiel I, van Mil EGAH, Verweij M, Vreugdenhil ACE. Weight Gain in Children during the COVID-19 Pandemic and the Protective Effect of Lifestyle Intervention in Children with Obesity. Obes Facts. 2022;15(4):600-608. doi: 10.1159/000525298. Epub 2022 May 31.

    PMID: 35640561DERIVED

  • van Dam MJCM, Pottel H, Vreugdenhil ACE. Creatinine-based GFR-estimating equations in children with overweight and obesity. Pediatr Nephrol. 2022 Oct;37(10):2393-2403. doi: 10.1007/s00467-021-05396-y. Epub 2022 Feb 24.

    PMID: 35211793DERIVED

  • Ten Velde G, Plasqui G, Dorenbos E, Winkens B, Vreugdenhil A. Objectively measured physical activity and sedentary time in children with overweight, obesity and morbid obesity: a cross-sectional analysis. BMC Public Health. 2021 Aug 17;21(1):1558. doi: 10.1186/s12889-021-11555-5.

    PMID: 34404361DERIVED

  • Rijks JM, Plat J, Dorenbos E, Penders B, Gerver WM, Vreugdenhil ACE. Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention. J Clin Endocrinol Metab. 2017 Jun 1;102(6):2051-2058. doi: 10.1210/jc.2016-3057.

    PMID: 28379580DERIVED

  • Rijks J, Karnebeek K, van Dijk JW, Dorenbos E, Gerver WJ, Stouthart P, Plat J, Vreugdenhil A. Glycaemic Profiles of Children With Overweight and Obesity in Free-living Conditions in Association With Cardiometabolic Risk. Sci Rep. 2016 Aug 18;6:31892. doi: 10.1038/srep31892.

    PMID: 27534260DERIVED

  • Rijks J, Penders B, Dorenbos E, Straetemans S, Gerver WJ, Vreugdenhil A. Pituitary response to thyrotropin releasing hormone in children with overweight and obesity. Sci Rep. 2016 Aug 3;6:31032. doi: 10.1038/srep31032.

    PMID: 27485208DERIVED

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

* Urine * Feces * Blood\&DNA * Liver ultrasound \& fibroscan * Lipidomics

MeSH Terms

Conditions

Pediatric ObesityOverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Anita Vreugdenhil, Dr

    Maastricht University Medical Center

    PRINCIPAL INVESTIGATOR

  • Luc Zimmermann, Prof.dr.

    Maastricht University Medical Center

    STUDY CHAIR

Central Study Contacts

Anita Vreugdenhil, Dr

CONTACT

0031 (0)43 387 5284a.vreugdenhil@mumc.nl

Kylie Karnebeek, Drs

CONTACT

0031 (0)43 387 4402

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 17, 2013

First Posted

March 19, 2014

Study Start

April 1, 2014

Primary Completion

April 1, 2023

Study Completion

April 1, 2023

Last Updated

April 30, 2020

Record last verified: 2020-04

Locations

NL(1)