Muscle Mass and Function in Chinese Adults

NCT02089971 | Completed

• 1 other identifier: BL23
• Study Type: observational
• Target: 412
• Locations: 1 country
• Sites: 2

Brief Summary

To describe the normal range of muscle mass and function in Chinese adults.

Conditions

Sarcopenia

Outcome Measures

Primary Outcomes (1)

• Total skeletal muscle mass

  Dual X-ray Absorptiometry (DXA)

  Test Visit 1 (~ Day 13)

Secondary Outcomes (3)

• Total body fat

  Test Visit 1 (~ Day 13)

• Total body fat free mass

  Test Visit 1 (~ Day 13)

• Total skeletal muscle mass

  Test Visit 1 (~ Day 13)

Study Arms (1)

Young Chinese adults

cross-sectional, observational study of community dwelling young Chinese adults

Eligibility Criteria

• Age: 25 Years - 34 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Cross-sectional, observational study of young Chinese adults

You may qualify if:

• Young adult ages between 25 and 34 years, inclusively.
• Adult is judged to be in good health as determined from his/her medical history as his/her self-report to the enrolling center personnel and as confirmed through a clinical examination by a physician.
• Adult with BMI between 18.5 to 26.9.
• Male or non-pregnant non-lactating female. Non-pregnant should be confirmed by urine pregnant test. And non-lactating is defined as postpartum more than 18 months.
• Subject has voluntarily signed and dated an informed consent form, approved by an Independent Ethics Committee/Institutional Review Board (IEC/IRB) prior to any participation in the study.

You may not qualify if:

• Subject who is heavy manual labor.
• Subject who is professional or semi-professional athlete or game player.
• Subject who is physical disabilities, such as loss of hand or foot or limbs or any physical disability which may affect the physical activities and affect the distribution of muscle mass by the opinion of the study physician.
• Subject has known chronic diseases such as endocrine system diseases (including type 1 or type 2 diabetes mellitus, or hyperthyroidism or hypothyroidism), cardiovascular diseases, liver diseases, and renal diseases as self-report.
• Subject who has active infection of TB, HIV and hepatitis as self-report.
• Subject who currently experiencing diarrhea or anorexia within 7days prior to the enrollment.
• Subject who has or plans for intensive physical activities 3 days prior to the scheduled BIA measurement.
• Subject who is thyroid malfunction (as serum fT4 level and/or serum TSH level out of the reference range of the lab)
• Subject has implanted electronic device, orthopedic metal implantations, such as pacemaker, cardiac defibrillator, or metal hip, metal knee joint, metal fracture internal fixation, etc.
• Subject is drug addiction or alcohol addiction.
• Subject is anemia (as blood hemoglobin level less than 120 g/L in males and 110 g/L in females).
• Subject is malnourished by study physician's opinion
• Subject has active cancers as self-report
• Subject has lost or gained more than 5% of body weight in the past 3 months
• Subject attends other clinical trials and is not approved by AN

Sponsors & Collaborators

• Abbott Nutrition: lead

Study Sites (2)

Peking Union Medical College Hospital

Beijing, 100730, China

Location

Shanghai 6th People's Hospital

Shanghai, 200233, China

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• Xianfeng Zhao, MD, PhD

  Abbott Nutrition China

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 14, 2014
• First Posted: March 18, 2014
• Study Start: March 1, 2014
• Primary Completion: October 1, 2014
• Study Completion: December 1, 2014
• Last Updated: January 19, 2015

Record last verified: 2015-01

Locations

CN (2)