NCT02082288

Brief Summary

Purpose of this study is to detect outcome of intracytoplasmic sperm injection (ICSI) according to EIOS

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
243

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Dec 2010

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2010

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2012

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

March 4, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 10, 2014

Completed
7 months until next milestone

Results Posted

Study results publicly available

October 16, 2014

Completed
Last Updated

January 26, 2015

Status Verified

January 1, 2015

Enrollment Period

1.8 years

First QC Date

March 4, 2014

Results QC Date

October 9, 2014

Last Update Submit

January 11, 2015

Conditions

Keywords

ICSI outcome

Outcome Measures

Primary Outcomes (1)

  • Clinical Pregnancy

    A clinical pregnancy will be determined by identifying the presence of a gestational sac at six weeks gestation on transvaginal ultrasonography.

    6 weeks

Study Arms (1)

Edessy ICSI Outcome Embryo Score

EXPERIMENTAL

ICSI

Other: Edessy ICSI Outcome Embryo Score

Interventions

EIOS: Age (ys) \>35 (0) 30-35 (1) \<30 (2) No of retrived oocyte \<5 (0) 5-9 (1) ≥ 10 (2) No of EC embryos \<2 (0) 2-4 (1) \>4 (2) No of good quality embryos \<3 (0) 3-5 (1) \>5 (2) No of embryos transferred -------- (0) ≤2 (1) \>2 (2)

Edessy ICSI Outcome Embryo Score

Eligibility Criteria

Age20 Years - 40 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age ≤ 40 years old. BMI \>25 - 30 kg/m2. Have two ovaries. Regular cycles. 1st ICSI cycle. Long midluteal GnRH protocol

You may not qualify if:

  • uterine factor as a cause of female factor infertility. pelvic masses or diseases (e.g: endometriosis, fibroids, hydro- salpnix, ...). history of medical disorders (e.g: hypertension, D.M, thyroid dysfunction, liver diseases, renal diseases,...).
  • azoospermia as a cause of male factor infertility.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

International Islamic Center for Population Studies and Research (IICPSR), Al-Azhar university

Cairo, Cairo Governorate, Egypt

Location

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Results Point of Contact

Title
wael mohamed hamed
Organization
al-azhar university

Study Officials

  • Mahmoud Edessy, MD

    Al-Azhar University

    PRINCIPAL INVESTIGATOR
  • Abd-Elnasr M Ali, MD

    Al-Azhar University

    PRINCIPAL INVESTIGATOR
  • Ahmed Fata, MD

    Al-Azhar University

    STUDY DIRECTOR
  • Wael M Hamed, MSc

    Al-Azhar University

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
al-azhar unversity (assuit), faculty of medicine, obstetrics and gynecology department

Study Record Dates

First Submitted

March 4, 2014

First Posted

March 10, 2014

Study Start

December 1, 2010

Primary Completion

September 1, 2012

Study Completion

September 1, 2012

Last Updated

January 26, 2015

Results First Posted

October 16, 2014

Record last verified: 2015-01

Locations