Predicting Acute Kidney Injury After Coronary Artery Bypass Graft

NCT02081261 | Completed

• 1 other identifier: 2013-12-116
• Study Type: observational
• Target: 877
• Locations: 1 country
• Sites: 1

Brief Summary

Acute kidney injury after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. There have been many studies reporting risk factor of acute kidney injury after cardiac surgery, but the influence of perioperative variables related to anesthesia and perioperative medication has not been evaluated fully. The investigators attempt to evaluate the influence of perioperative clinical variables including preoperative medication, preoperative albumin level, uric acid concentration, anesthesia technique, use of hydroxyethyl starch, blood glucose level, intraoperative medication, perioperative cardiac function (systolic and diastolic function) and hemodynamic variables during surgery on the incidence of acute kidney injury after coronary artery bypass graft.

Conditions

Coronary Artery Bypass Surgery; Acute Kidney Injury; Creatinine; Mortality

Keywords

coronary artery bypass surgery; acute kidney injury; creatinine; mortality

Outcome Measures

Primary Outcomes (1)

• Acute kidney injury diagnosis defined by KDIGO criteria

  Acute kidney injury diagnosis defined by KDIGO criteria (Stage 1, 2, 3) during seven days after surgery

  during 7 days after surgery

Secondary Outcomes (1)

• Acute kidney injury as defined by AKIN (acute kidney injury network) criteria

  within 48 hours after surgery

Study Arms (1)

Coronary artery bypass surgery

patients who underwent coronary artery bypass surgery between 2010 and 2012 in Samsung Medical Center

Procedure: Coronary artery bypass surgery

Interventions

Coronary artery bypass surgery PROCEDURE

coronary artery bypass surgery

Coronary artery bypass surgery

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who underwent coronary artery bypass surgery during between 2010 and 2012 in Samsung Medical Center

You may qualify if:

• patients who underwent coronary artery bypass surgery during between 2010 and 2012 in Samsung Medical Center

You may not qualify if:

• lack of postoperative creatinine or urine output data
• patients who expired within 24hours after surgery

Sponsors & Collaborators

• Samsung Medical Center: lead

Study Sites (1)

Samsung Medical Center

Seoul, 135-710, South Korea

Location

MeSH Terms

Conditions

Acute Kidney Injury

Interventions

Coronary Artery Bypass

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Intervention Hierarchy (Ancestors)

Myocardial Revascularization; Cardiac Surgical Procedures; Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Vascular Grafting; Vascular Surgical Procedures; Thoracic Surgical Procedures

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: March 5, 2014
• First Posted: March 7, 2014
• Study Start: January 1, 2014
• Primary Completion: February 1, 2016
• Study Completion: February 1, 2016
• Last Updated: June 16, 2016

Record last verified: 2016-06

Locations

KR (1)