Incidence and Risk Factors of Refeeding Syndrome
1 other identifier
observational
79
1 country
1
Brief Summary
The main objective of this observational survey was to determine the incidence rate of refeeding phenomena (RFF) (defined as any decline in p-phosphate) and RFS (defined as any decline in p-phosphate with additional development of any of the following clinical symptoms: oedema, confusion, dyspnoea, hypotension, arrhythmia, seizures) among recently admitted or referred HNC patients to the Department of Otorhinolaryngology for surgery. The second objective was to determine if informations at admittance could identify HNC patients at high risk of developing RFF and RFS.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2011
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2011
CompletedFirst Submitted
Initial submission to the registry
February 24, 2014
CompletedFirst Posted
Study publicly available on registry
February 27, 2014
CompletedFebruary 27, 2014
February 1, 2014
6 months
February 24, 2014
February 26, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Decrease in plasma phosphate after start of feeding
Plasma phosphate measured every day the initial day of feeding after admission
1 week
Secondary Outcomes (1)
Occurence of relevant clinical symptoms along with a decrease in plasma phosphate
1 week
Study Arms (1)
Head -Neck cancer patients, no intervention
Interventions
Eligibility Criteria
Referred for surgery with head and neck cancer
You may qualify if:
- Head and Neck Cancer
You may not qualify if:
- Not able to understand and speak Danish, having severe dementia and/or renal impairment (women: p-creatinine \> 180 μmol/l, men: p-creatinine \> 200 μmol/l).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Clinic for Ear, Nose and Throat Surgery, Rigshospital
Copenhagen, 2100 Cph OE, Denmark
Related Publications (1)
Rasmussen SO, Kristensen MB, Wessel I, Andersen JR. Incidence and Risk Factors of Refeeding Syndrome in Head and Neck Cancer Patients-An Observational Study. Nutr Cancer. 2016 Nov-Dec;68(8):1320-1329. doi: 10.1080/01635581.2016.1225103. Epub 2016 Sep 28.
PMID: 27682582DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor, Senior Physician
Study Record Dates
First Submitted
February 24, 2014
First Posted
February 27, 2014
Study Start
February 1, 2011
Primary Completion
August 1, 2011
Study Completion
August 1, 2011
Last Updated
February 27, 2014
Record last verified: 2014-02