NCT02072395

Brief Summary

The purpose of the study is to assess the efficacy of a hybrid laparoscopic surgical procedure for treatment of morbid obesity, Gastric Plication (G)) and Gastric Banding.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Feb 2012

Typical duration for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2012

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

February 24, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 26, 2014

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
Last Updated

February 20, 2017

Status Verified

February 1, 2017

Enrollment Period

4.3 years

First QC Date

February 24, 2014

Last Update Submit

February 16, 2017

Conditions

Keywords

morbid obesitybariatric surgerygastric bandinggastric plication

Outcome Measures

Primary Outcomes (2)

  • Weight loss

    The primary endpoint is weight loss two years post-surgery.

    Two years

  • Complications

    Intra and post-operative complications will be tracked.

    2 years

Study Arms (1)

Band/Plication

EXPERIMENTAL

Treatment -- band/plication

Procedure: Plication

Interventions

PlicationPROCEDURE

Plication of the stomach will be performed in conjunction with placement of a gastric band.

Band/Plication

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18-70
  • BMI \> or = to 30 and co-morbid conditions or BMI \> or = to 40
  • Ability to provide informed consent
  • Willingness to commit to long-term follow-up

You may not qualify if:

  • Inability to provide informed consent
  • Presence of metabolic or medically correctable cause(s) for obesity, such as untreated hypothyroidism or Prader-Willi
  • Contraindications to surgery such as myocardial infarction within last 6 months, end stage renal or liver disease, current infection, or other disease states contraindicative to surgery, in the principal investigator's opinion
  • Pregnancy
  • Plan to become pregnant within two years post-surgery
  • Current addiction to drugs or alcohol
  • Previous history of any type of bariatric surgery (de novo group only)
  • Hiatal hernia \> 3 cm

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Ohio State University Wexner Medical Center

Columbus, Ohio, 43210, United States

Location

Related Publications (1)

  • Chaudhry UI, Osayi SN, Suzo AJ, Noria SF, Mikami DJ, Needleman BJ. Laparoscopic adjustable gastric banded plication: case-matched study from a single U.S. center. Surg Obes Relat Dis. 2015 Jan-Feb;11(1):119-24. doi: 10.1016/j.soard.2014.05.030. Epub 2014 Jun 4.

    PMID: 25443058BACKGROUND

MeSH Terms

Conditions

Obesity, Morbid

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Bradley J Needleman, MD

    Ohio State University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 24, 2014

First Posted

February 26, 2014

Study Start

February 1, 2012

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

February 20, 2017

Record last verified: 2017-02

Locations